Profile

New User

New to Graphy Publications? Create an account to get started today.

Registered Users

Have an account? Sign in now.

How to Cite | Author Information | Publication History | Funding Information
International Journal of Pharmaceutical Sciences Research Volume 7 (2020), Article ID 7:IJPSR-137, 2 pages
https://doi.org/10.15344/2394-1502/2020/137
Short Communication
Discovery of Oosporein as a New Inhibitor of Influenza Virus Cap-snatching Activity

Nobuhiro Koyama1,2*, Yoshio Shibagaki3, Mitsuru Okuwaki3, Seisuke Hattori3 and Hiroshi Tomoda1,2*

1Department of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, Japan
2Medicinal Research Laboratories, School of Pharmacy, Kitasato University, Japan
3Division of Biochemistry, School of Pharmacy, Kitasato University, Japan
Dr. Nobuhiro Koyama, Department of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan; E-mail: koyaman@pharm.kitasato-u.ac.jp
Dr. Hiroshi Tomoda, Department of Microbial Chemistry, Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan; E-mail: tomodah@pharm.kitasato-u.ac.jp
10 June 2020; 04 July 2020; 05 July 2020
Koyama N, Shibagaki Y, Okuwaki M, Hattori S, Tomoda H, et al. (2020) Discovery of Oosporein as a New Inhibitor of Influenza Virus Cap-snatching Activity. Int J Pharma Sci Res 7: 137. doi: https://doi.org/10.15344/2456-4028/2020/137
This work was supported by grant 15K07867 (NK) from the Ministry of Education, Culture, Sport, Science, and Technology, Japan.
© 2020 Mal et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

References

  1. Koyama N, Shigeno S, Kanamoto A, Tomoda H (2020) Steffimycin E, a new anti-mycobacterial agent against Mycobacterium avium complex, produced by Streptomyces sp. OPMA02852. J Antibiot 73: 581-584. View
  2. Koyama N, Tomoda H (2019) MS network-based screening for new antibiotics discovery. J Antibiot (Tokyo) 72: 54-56. View
  3. Floros DJ, Jensen PR, Dorrestein PC, Koyama N (2016) A metabolomics guided exploration of marine natural product chemical space. Metabolomics 12: 145. View
  4. Tominaga T, Uchida R, Koyama N, Tomoda H (2018) Anti-Rhizopus activity of tanzawaic acids produced by the hot spring-derived fungus Penicillium sp. BF-0005. J Antibiot 71: 626-632. View
  5. Hosoda K, Koyama N, Kanamoto A, Tomoda H (2019) Discovery of Nosiheptide, Griseoviridin, and Etamycin as Potent Anti-Mycobacterial Agents against Mycobacterium avium Complex. Molecules 24:E1495. View
  6. Love BE, Bonner-Stewart J, Forrest LA. (2009) An efficient synthesis of oosporein. Tetrahed Lett 50:5050-5052. View
  7. Shibagaki Y, Ikuta N, Iguchi S, Takaki K, Watanabe S, et al. (2014) An efficient screening system for influenza virus cap-dependent endonuclease inhibitors. J Virol Methods 202: 8-14. View
  8. Klumpp K, Hooker L, Handa B (2001) Influenza virus endoribonuclease. Methods Enzymol 342: 451-466. View
  9. Wakai C, Iwama M, Mizumoto K, Nagata K (2011) Recognition of cap structure by influenza B virus RNA polymerase is less dependent on the methyl residue than recognition by influenza A virus polymerase. J Virol 85: 7504-7512. View
  10. Tomassini J, Selnick H, Davies ME, Armstrong ME, Baldwin J, et al. (1994) Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds. Antimicrob Agents Chemother 38: 2827-2837.
  11. Terry BJ, Liu WC, Cianci CW, Proszynski E, Fernandes P, et al. (1992) Inhibition of herpes simplex virus type 1 DNA polymerase by the natural product oosporein. J Antibiot 45: 286-288. View
Best viewed in Mozilla Firefox, Google Chrome, Safari, Above IE 9.0 version
Privacy Policy | Copyright & Permissions
Copyright © 2013-2025 Graphy Publications, All Rights Reserved.