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International Journal of Pharmaceutical Sciences Research Volume 3 (2016), Article ID 3:IJPSR-119, 6 pages
https://doi.org/10.15344/2394-1502/2016/119
Research Article
The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment

Raoul Saggini1*, A Saggini2, Sm Carmignano3, T Palermo3, G Barassi4, Mg Onesti5, Rg Bellomo6 and N Scuderi5

1Full Professor, Physical and Rehabilitation Medicine, Department of Medical Oral and Biotechnological Sciences, Director of the School of Specialty in Physical and Rehabilitation Medicine,“Gabriele d’Annunzio” University, Chieti, Pescara, Italy National Coordinator of Schools of Specialty in Physical and Rehabilitation Medicine
2Anatomic Pathology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy Dermatology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy
3School of Specialty in Physical and Rehabilitation Medicine, “Gabriele d’Annunzio” University, Chieti, Pescara, Italy
4PhD, LectureFaculty of Physiotherapy “G.d’Annunzio” University-Chieti, Italy
5Department of Plastic and Reconstructive Surgery, "Sapienza" University, Policlinico Umberto I, Rome, Italy
6Associated Professor, Physical and Rehabilitation Medicine, Department of Medicine and Sciences of Aging, “Gabriele d’Annunzio” University, Chieti, Pescara, Italy
Prof. Raoul Saggini, Director of the School of Specialty in Physical and Rehabilitation Medicine,“Gabriele d’Annunzio” University, Chieti, Pescara, Italy; E-mail: saggini@unich.it
05 October 2016; 19 December 2016; 21 December 2016
Saggini R, Saggini A, Carmignano SM, Palermo T, Barassi G, et al. (2016) The Role of Extracorporeal Shock Wave Therapy and Manual Lymphatic Drainage in Chronic Ulcers Treatment. Int J Pharma Sci Res 3: 119. doi: https://doi.org/10.15344/2394-1502/2016/119

Abstract

Introduction: Chronic wounds are a major, functionally-limiting medical problem impairing quality of life for millions of people each year. Extracorporeal shock wave therapy (ESWT) may accelerate and improve wound repair. Some authors investigated the optimal session number of ESWT in rat models.
Aim: Purpose of this study was to verify the effectiveness of two temporal modalities of ESWT administration in chronic ulcers.
Materials and methods: 84 subjects with chronic ulcers were enrolled. They were divided into 2 groups according to the absence or presence of associated lymphedema. Each group was divided with a stratified randomization into two subgroups receiving the same total energy of ESWT (2640 Mj) but with different temporal modality during the week.
Results: Our results show, at the end of the 5 weeks treatment, a statistically significant reductionof wounds area and pain in the groups which received the ESWT fractioned in 2 weekly steps (2 x 1320 Mj) and reduction of limb circumference in subjects with lymphedema.
Discussion: By fractioning energy in 2 weekly steps probably there is greater regenerative activation. This type of application cannot be generalized, it could be a best choice in diabetic ulcers, even in the presence of lymphedema. The kwnoledge relative to the efficacy of ESWT in treatment of chronic wounds has had over the years a consolidation process, instead the modulation of time treatment can be considered as a new borders for clinical studies.