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International Journal of Nursing & Clinical Practices Volume 7 (2020), Article ID 7:IJNCP-318, 4 pages
https://doi.org/10.15344/2394-4978/2020/318
Case Study
Vitamin D3 Supplementation Ameliorates Typical Clinical Symptoms in Children with Autism Spectrum Disorder in Japan: A Case Study

Noboru Hasegawa1*, Takako Yamada2 and Miyako Mochizuki3

1Department of Health and Medical Sciences, Ishikawa Prefectural Nursing University, 1-1 Gakuendai, Kahoku, Ishikawa 929-1210, Japan
2Department of Occupational Therapy, Bukkyo University, 7, Higashitoganoo-cho, Nishinokyo, Nakagyo-ku, Kyoto604-8418, Japan
3Kyoto Bunkyo Junior College, 80 Senzoku, Makishima-cho, Uji, Kyoto 611-0041, Japan
Prof. Noboru Hasegawa, Department of Health and Medical Sciences, Ishikawa Prefectural Nursing University, 1-1 Gakuendai, Kahoku, Ishikawa 929-1210, Japan, Tel: +81-76-281-8300, Fax: +81-281-8319; E-mail: hsgwn@ishikawa-nu.ac.jp
13 December 2019; 07 January 2020; 09 January 2020
Hasegawa N, Yamada T, Mochizuki M (2020) Vitamin D3 Supplementation Ameliorates Typical Clinical Symptoms in Children with Autism Spectrum Disorder in Japan: A Case Study. Int J Nurs Clin Pract 7: 318. doi: https://doi.org/10.15344/2394-4978/2020/318

Abstract

Background: We studied the effects of vitamin D3 supplementation on serum levels of 25-hydroxyvitamin D and typical clinical symptoms in children with autism spectrum disorder (ASD).
Methods: We enrolled 5 male and 1femaleJapanesechildren with ASD aged 3years. Serum25-hydroxy vitamin D was measured prior to after 9months of supplementation with oral vitamin D3 oil (2μg /day of vitamin D3, corresponding to twice the daily requirement). The Childhood Autism Rating Scale (CARS), Short Sensory Profile (SSP), Vineland-II were used to assess the severity of autism-related traits. Data were analyzed using a Wilcoxon test.
Results: The 25-hydroxy vitamin D level were<20 ngml (deficient) in 2 children,>=20 ng/mL and <30ng> Conclusion: These findings show that vitamin D supplementation might ameliorate typical clinical symptoms in children with autism spectrum disorder.