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International Journal of Clinical Nutrition & Dietetics Volume 2 (2016), Article ID 2:IJCND-111, 6 pages
https://doi.org/10.15344/2456-8171/2016/111
Research Article
Gender Differences in the Alteration of Obesogenic Environments in Korean Children According to GNB3 Polymorphism

Yunkyoung Lee1, Seong-min Park2,3, Myoungsook Lee 3*

1Department of Food Science and Nutrition, Jeju National University, Jeju, South Korea
2Imported Food Analysis Team, Ministry of Food Drug Safety, Gyeongin Regional, Food & Drug Administration, South Korea.
3Research Institute of Obesity Sciences and Department of Food and Nutrition, Sungshin Women’s university, Seoul, South Korea
Dr. Myoungsook Lee, Research Institute of Obesity Sciences and Department of Food and Nutrition, Sungshin Women’s university, Seoul, South Korea, Tel : 82-2-920-7211; E-mail: mlee@sungshin.ac.kr
17 April 2016; 07 July 2016; 09 July 2016
Lee Y, Park S, Lee M (2016) Gender Differences in the Alteration of Obesogenic Environments in Korean Children According to GNB3 Polymorphism. Int J Clin Nutr Diet 2: 111. doi: https://doi.org/10.15344/2456-8171/2016/111
This study was supported by Korea Food & Drug Administration (11162KFDA162) and National Research Foundation of Korea grant funded by the Korea government (MSIP) (2014R1A2A1A11049611/1).

References

  1. Moon JS (2011) Secular trends of body sizes in korean children and adolescents: From 1965 to 2010. Korean J Pediatr 54: 436-442 [CrossRef] [Google Scholar] [PubMed]
  2. Reilly JJ, Methven E, McDowell ZC, Hacking B, Alexander D, et al. (2003) Health consequences of obesity. Arch Dis Child 88: 748-752 [CrossRef] [Google Scholar]
  3. Bouchard C (1991) Current understanding of the etiology of obesity: Genetic and nongenetic factors. Am J Clin Nutr 53: 1561S-1565S [CrossRef] [Google Scholar] [PubMed]
  4. Comuzzie AG, Allison DB (1998) The search for human obesity genes. Science 280: 1374-1377 [CrossRef] [Google Scholar] [PubMed]
  5. Martínez-Hernández A, Enriquez L, Moreno-Moreno MJ, Marti A (2007) Genetics of obesity. Public Health Nutr 10: 1138-1144 [CrossRef]
  6. Hamm HE (1998) The many faces of G protein signaling. J Biol Chem 273: 669-672 [CrossRef] [Google Scholar] [PubMed]
  7. Oldham WM, Hamm HE (2008) Heterotrimeric G protein activation by G-protein-coupled receptors. Nat Rev Mol Cell Biol 9: 60-71 [CrossRef] [Google Scholar] [PubMed]
  8. Tesmer JJ (2010) The quest to understand heterotrimeric G protein signaling. Nat Struct Mol Biol 17:650-652 [CrossRef] [Google Scholar] [PubMed]
  9. Thathiah A, De Strooper B (2011) The role of G protein-coupled receptors in the pathology of alzheimer's disease. Nat Rev Neurosci 12: 73-87 [CrossRef] [Google Scholar] [PubMed]
  10. Brinks HL, Eckhart AD (2010) Regulation of GPCR signaling in hypertension. Biochim Biophys Acta 1802: 1268-1275 [CrossRef] [Google Scholar] [PubMed]
  11. Lappano R,Maggiolini M (2011) G protein-coupled receptors: Novel targets for drug discovery in cancer. Nat Rev Drug Discovery 10: 47-60 [CrossRef] [Google Scholar] [PubMed]
  12. Vassart G, Costagliola S (2011) G protein-coupled receptors: Mutations and endocrine diseases. Nat Rev Endocrinol 7: 362-372 [CrossRef] [Google Scholar] [PubMed]
  13. Rosskopf D, Busch S, Manthey I, Siffert W (2000) G protein beta 3 gene: Structure, promoter, and additional polymorphisms. Hypertension 36: 33- 41 [CrossRef] [Google Scholar] [PubMed]
  14. Siffert W, Rosskopf D, Siffert G, Busch S, Moritz A, et al. (1998) Association of a human G-protein beta3 subunit variant with hypertension. Nat Genet 18: 45-48 [CrossRef] [Google Scholar] [PubMed]
  15. Siffert W, Naber C, Walla M, Ritz E (1999) G protein β3 subunit 825T allele and its potential association with obesity in hypertensive individuals. J Hypertens 17: 1095-1098 [CrossRef] [Google Scholar] [PubMed]
  16. Klenke S, Kussmann M, Siffert W (2011) The GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression. Pharmacogenet Genomics 21: 594-606 [CrossRef] [Google Scholar] [PubMed]
  17. Hegele RA, Harris SB, Hanley AJ, Cao H, Zinman B (1998) G protein beta3 subunit gene variant and blood pressure variation in canadian oji-cree. Hypertension 32: 688-692 [CrossRef] [Google Scholar] [PubMed]
  18. Siffert W, Rosskopf D, Erbel R (2000) Genetic polymorphism of the G-protein beta3 subunit, obesity and essential hypertension. Herz 25: 26- 33 [Google Scholar] [PubMed]
  19. Poch E, Giner V, Gonzalez-Nunez D, Coll E, Oriola J, et al. (2002) Association of the G protein beta3 subunit T allele with insulin resistance in essential hypertension. Clin Exp Hypertens 24: 345-353 [PubMed]
  20. Brand E, Wang J, Herrmann S, Staessen JA (2003) An epidemiological study of blood pressure and metabolic phenotypes in relation to the Gβ3C825T polymorphism. J Hypertens 21: 729-737 [Google Scholar]
  21. Siffert W, Forster P, Jockel KH, Mvere DA, Brinkmann B, et al. (1999) Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in caucasian, chinese, and black african individuals. J Am Soc Nephrol 10: 1921-1930 [Google Scholar] [PubMed]
  22. Li B, Ge D, Wang Y, Zhao W, Zhou X, et al. (2005) G protein β3 subunit gene variants and essential hypertension in the northern chinese han population. Ann Hum Genet 69: 468-473 [CrossRef] [Google Scholar] [PubMed]
  23. Bae Y, Park C, Han J, Hong Y, Song H, et al. (2007) Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in koreans. J Hum Hypertens 21:159-166 [CrossRef] [Google Scholar] [PubMed]
  24. Ko KD, Kim KK, Suh HS, Hwang IC (2014) Associations between the GNB3 C825T polymorphism and obesity-related metabolic risk factors in korean obese women. J Endocrinol Invest 37: 1117-1120 [CrossRef] [Google Scholar] [PubMed]
  25. Hwang IC, Kim KK, Ahn HY, Suh HS, Oh SW (2013) Effect of the G-protein beta3 subunit 825T allele on the change of body adiposity in obese female. Diabetes Obes Metab 15: 284-286 [CrossRef] [Google Scholar] [PubMed]
  26. Babu A, Fogelfeld L (2006) Metabolic syndrome and prediabetes. Dis Mon 52: 55-144 [CrossRef] [PubMed]
  27. Vekic J, Topic A, Zeljkovic A, Jelic-Ivanovic Z, Spasojevic-Kalimanovska V (2007) LDL and HDL subclasses and their relationship with framingham risk score in middle-aged serbian population. Clin Biochem 40:310-316 [CrossRef] [Google Scholar] [PubMed]
  28. Camont L, Chapman MJ, Kontush A (2011) Biological activities of HDL subpopulations and their relevance to cardiovascular disease. Trends Mol Med 17: 594-603 [CrossRef] [Google Scholar] [PubMed]
  29. Lamarche B, Moorjani S, Cantin B, Dagenais GR, Lupien PJ, et al. (1997) Associations of HDL2 and HDL3 subfractions with ischemic heart disease in men. prospective results from the quebec cardiovascular study. Arterioscler Thromb Vasc Biol 17: 1098-1105 [CrossRef] [Google Scholar] [PubMed]
  30. Lee M, Jang Y, Kim K, Cho H, Jee SH, et al. (2010) Relationship between HDL3 subclasses and waist circumferences on the prevalence of metabolic syndrome: KMSRI-seoul study. Atherosclerosis 213:288-293 [CrossRef] [Google Scholar] [PubMed]
  31. Moon JS, Lee SY, Nam CM, Choi J, Choe B, et al. (2008) 2007 korean national growth charts: Review of developmental process and an outlook. Korean J Pediatr 51: 1-25 [Google Scholar]
  32. Seo J, Cho Y, Kang J, Hur Y, Park H, et al. (2013) New diagnostic criteria for obesity and overweight in korean children and adolescents using 2007 korean national growth charts. Obesity Research & Clinical Practice 7: e182-e189 [CrossRef] [Google Scholar] [PubMed]
  33. Lee M, Kim MK, Kim SM, Park H, Park CG, et al. (2015) Gender-based differences on the association between salt-sensitive genes and obesity in korean children aged between 8 and 9 years. PLoS One 10: e0120111 [CrossRef] [Google Scholar] [PubMed]
  34. Perusse M, Pascot A, Despres JP, Couillard C, Lamarche B (2001) A new method for HDL particle sizing by polyacrylamide gradient gel electrophoresis using whole plasma. J Lipid Res 42: 1331-1334 [Google Scholar] [PubMed]
  35. Willett WC, Howe GR,Kushi LH (1997) Adjustment for total energy intake in epidemiologic studies. Am J ClinNutr 65:1220S-1228S [CrossRef] [Google Scholar] [PubMed]
  36. Frey UH, Moebus S, Mohlenkamp S, Kalsch H, Bauer M, et al. (2014) GNB3 gene 825 TT variant predicts hard coronary events in the populationbased heinz nixdorf recall study. Atherosclerosis 237: 437-442 [CrossRef] [Google Scholar] [PubMed]
  37. Garcés C, Gutierrez-Guisado J, Benavente M, Cano B, Viturro E, et al. (2005) Obesity in spanish schoolchildren: Relationship with lipid profile and insulin resistance. Obes Res 13: 959-963 [CrossRef] [Google Scholar] [PubMed]
  38. Numata M (2004) High density lipoprotein particle size in children: Relation to atherogenic dyslipidemia. Clin Pediatr Endocrinol 13: 1 [CrossRef] [Google Scholar] [PubMed]
  39. Hegele RA, Anderson C, Young TK, Connelly PW (1999) G-protein beta3 subunit gene splice variant and body fat distribution in nunavut inuit. Genome Res 9: 972-977 [CrossRef] [Google Scholar] [PubMed]
  40. Benjafield AV, Lin RC, Dalziel B, Gosby AK,Caterson ID, et al. (2001) G-protein beta3 subunit gene splice variant in obesity and overweight. Int J Obes Relat Metab Disord 25: 777-780 [CrossRef] [Google Scholar] [PubMed]
  41. Rankinen T, Rice T, Leon AS, Skinner JS, Wilmore JH, et al. (2002) G protein beta 3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE family study. Physiol Genomics 8: 151-157 [CrossRef] [Google Scholar] [PubMed]