Exercise Training Prevent Decrease of Muscle Strength in Otsuka Long- Evans Tokushima Fatty Rats: A Preliminary Study

doi:10.15344/2455-7498/2016/121

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International Journal of Physical Therapy & Rehabilitation Volume 2 (2016), Article ID 2:IJPTR-121, 3 pages
https://doi.org/10.15344/2455-7498/2016/121

Short Communication
Special Issue: Various Approaches for Rehabilitation Science

Exercise Training Prevent Decrease of Muscle Strength in Otsuka Long- Evans Tokushima Fatty Rats: A Preliminary Study

Toru Tamaki^*, Masako Ikutomo, Satomi Arakawa, Junya Komagata, Masatoshi Niwa and Ken Muramatsu

¹Department of Physical Therapy, Health Science University, Yamanashi, Japan
²Department of Occupational Therapy, Kyorin University, Tokyo, Japan

Corresponding Author Details: Dr. Toru Tamaki Department of Physical Therapy, Health Science University, 7187 Kodachi, Fujikawaguchiko, Yamanashi 401- 0380, Japan; Tel: +81 555 83 5298; E-mail: toru-tamaki@kenkoudai.ac.jp

Received: 13 September 2016; Accepted: 21 October 2016; Published: 24 October 2016

Citation: Tamaki T, Ikutomo M, Arakawa S, Komagata J, Niwa M, et al. (2016) Exercise Training Prevent Decrease of Muscle Strength in Otsuka Long-Evans Tokushima Fatty Rats: A Preliminary Study. Int J Phys Ther Rehab 2: 121. doi: https://doi.org/10.15344/2455-7498/2016/121

Funding: This work was supported by Research Grant of Health Science University.

Copyright: © 2016 Jigami et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Decrease of muscle strength around knee and ankle are considered to contribute several movement disorders in diabetic patient such as an increased risk of falling, altered gait and balance, and increased body sway. In this study, we examine the effect of exercise training on skeletal muscle of type 2 diabetic models.
Methods: Otsuka Long–Evans Tokushima fatty (OLEFT) rats, type 2 diabetic models, were divided into an exercise training group (OLETF-EX, n = 3) and a sedentary group (OLETF-SED, n = 3), while Long– Evans Tokushima Otsuka (LETO) rats were used as a control group (LETO-SED, n = 4). The OLETF-EX rats were trained on a treadmill five times a week for 15 weeks. Data were subjected to two-tailed multiple t-tests with Bonferroni correction following an ANOVA.
Results: The muscle force per body weight was significantly lower tension in MG muscle of OLETFSED animals than LETO-SED animals. On the other hand, twitch tensions of OLETF-EX animals were preserved.
Conclusion: These data suggest that exercise training prevent decrease of muscle strength in type 2 diabetic model.

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