Profile
International Journal of Clinical Research & Trials Volume 4 (2019), Article ID 4:IJCRT-134, 07 pages
https://doi.org/10.15344/2456-8007/2019/134
Original Article
Non-invasive Brain Stimulation Paired with Standard Physical Therapy in Parkinson's Disease: A Pilot Feasibility Trial

Milton C. Biagioni1*, Estelle C. Gallo2, Andre Y. Son1, Kush Sharma1, Stephen J. Fischer2, Hamzeh A. Migdadi1, Shashank Agarwal1, Tara M. Biller1, Raphaela S. Sills1, Andrew S. Feigin1, Alessandro Di Rocco1 and Alberto Cucca1

1The Marlene and Paolo Fresco Institute for Parkinson’s and Movement Disorders, Department of Neurology, New York University School of Medicine, USA
2Rusk Rehabilitation, Department of Rehabilitation Medicine, New York University School of Medicine, New York, USA
Dr. Milton C. Biagioni, The Marlene and Paolo Fresco Institute for Parkinson’s and Movement Disorders, Department of Neurology, New York University School of Medicine, New York, USA; E-mail: milton.biagioni@nyumc.org
29 December 2018; 15 April 2019; 17 April 2019
Biagioni MC, Gallo EC, Son AY, Sharma K, Fischer SJ, et al. (2019) Noninvasive Brain Stimulation Paired with Standard Physical Therapy in Parkinson’s Disease: A Pilot Feasibility Trial. Int J Clin Res Trials 4: 134. doi: https://doi.org/10.15344/2456-8007/2019/134

References

  1. Tysnes OB, Storstein A (2017) Epidemiology of Parkinson's disease. J Neural Transm (Vienna) 124: 901-905 [CrossRef] [PubMed]
  2. Marras C, Beck JC, Bower JH, Roberts E, Rith B, et al. (2018) Prevalence of Parkinson's disease across North America. NPJ Parkinson's disease 4: 21 [Google Scholar]
  3. Beitz JM (2014) Parkinson's disease: a review. Front Biosci 6: 65-74 [PubMed]
  4. Hely MA, Reid WG, Adena MA, Halliday GM, Morris JG, et al. (2008) The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years. Mov Disord 23: 837-844 [CrossRef] [Google Scholar] [PubMed]
  5. Marinelli L, Crupi D, Di Rocco A, Bove M, Eidelberg D, et al. (2009) Learning and consolidation of visuo-motor adaptation in Parkinson's disease. Parkinsonism Relat Disord 15: 6-11 [CrossRef] [Google Scholar] [PubMed]
  6. Muslimovic D, Post B, Speelman JD, De Haan RJ, Schmand B, et al. (2009) Cognitive decline in Parkinson's disease: a prospective longitudinal study. J Int Neuropsychol Soc 15: 426-437 [CrossRef] [Google Scholar] [PubMed]
  7. Owen AM, Doyon J, Dagher A, Sadikot A, Evans AC, et al. (1998) Abnormal basal ganglia outflow in Parkinson's disease identified with PET. Implications for higher cortical functions. Brain 121: 949-965 [CrossRef] [Google Scholar] [PubMed]
  8. Wu T, Hallett M (2008) Neural correlates of dual task performance in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 79: 760- 766 [CrossRef] [Google Scholar] [PubMed]
  9. Pillon B, Dubois B, Cusimano G, Bonnet AM, Lhermitte F, et al. (1989) Does cognitive impairment in Parkinson's disease result from non-dopaminergic lesions? J Neurol Neurosurg Psychiatry 52: 201-206 [CrossRef] [Google Scholar] [PubMed]
  10. Rascol O, Payoux P, Ory F, Ferreira JJ, Brefel-Courbon C, et al. (2003) Limitations of current Parkinson's disease therapy. Annals of neurology 3: 3-12 [CrossRef] [Google Scholar] [PubMed]
  11. Domellof ME, Forsgren L, Elgh E (2013) Persistence of associations between cognitive impairment and motor dysfunction in the early phase of Parkinson's disease. J Neurol 260: 2228-2236 [CrossRef] [Google Scholar] [PubMed]
  12. Jankovic J (2015) Gait disorders. Neurologic clinics 33: 249-268 [CrossRef] [PubMed]
  13. Pinter B, Diem-Zangerl A, Wenning GK, Scherfler C, Oberaigner W, et al. (2015) Mortality in Parkinson's disease: a 38-year follow-up study. Mov Disord 30: 266-269 [CrossRef] [Google Scholar] [PubMed]
  14. Wenning GK, Ebersbach G, Verny M, Chaudhuri KR, Jellinger K, et al. (1999) Progression of falls in postmortem-confirmed parkinsonian disorders. Mov Disord 14: 947-950 [CrossRef] [Google Scholar] [PubMed]
  15. States RA, Sweeny TL, Rossi A, Spierer DK, Salem Y, et al. (2017) Physical Functioning After 1, 3, and 5 Years of Exercise Among People With Parkinson's Disease: A Longitudinal Observational Study. J Geriatr Phys Ther 40: 127-134 [CrossRef] [Google Scholar] [PubMed]
  16. Abbruzzese G, Marchese R, Avanzino L, Pelosin E (2016) Rehabilitation for Parkinson's disease: Current outlook and future challenges. Parkinsonism Relat Disord 1: 60-64 [CrossRef] [Google Scholar] [PubMed]
  17. Frazzitta G, Balbi P, Maestri R, Bertotti G, Boveri N, et al. (2013) The beneficial role of intensive exercise on Parkinson disease progression. Am J Phys Med Rehabil 92: 523-532 [CrossRef] [Google Scholar] [PubMed]
  18. Cramer SC, Sur M, Dobkin BH, O'Brien C, Sanger TD, et al. (2011) Harnessing neuroplasticity for clinical applications. Brain 134: 1591-1609 [CrossRef] [Google Scholar] [PubMed]
  19. Rossi S, Hallett M, Rossini PM, Pascual-Leone A (2009) Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol 120: 2008-2039 [CrossRef] [Google Scholar] [PubMed]
  20. Ahmed MA, Darwish ES, Khedr EM, El Serogy YM, Ali AM, et al. (2012) Effects of low versus high frequencies of repetitive transcranial magnetic stimulation on cognitive function and cortical excitability in Alzheimer's dementia. J Neurol 259: 83-92 [CrossRef] [Google Scholar] [PubMed]
  21. Narayana S, Zhang W, Rogers W, Strickland C, Franklin C, et al. (2014) Concurrent TMS to the primary motor cortex augments slow motor learning. NeuroImage 3: 971-984 [CrossRef] [Google Scholar] [PubMed]
  22. Reis J, Swayne OB, Vandermeeren Y, Camus M, Dimyan MA, et al. (2008) Contribution of transcranial magnetic stimulation to the understanding of cortical mechanisms involved in motor control. J Physiol 586: 325-351 [CrossRef] [Google Scholar] [PubMed]
  23. Tanaka S, Sandrini M, Cohen LG (2011) Modulation of motor learning and memory formation by non-invasive cortical stimulation of the primary motor cortex. Neuropsychol Rehabil 21: 650-675 [CrossRef] [Google Scholar] [PubMed]
  24. Biagioni MC, Sharma K, Migdadi HA, Cucca A. Non-Invasive Neuromodulation Therapies for Parkinson’s Disease. IntechOpen [Google Scholar]
  25. Moisello C, Blanco D, Fontanesi C, Lin J, Biagioni M, et al. (2015) TMS enhances retention of a motor skill in Parkinson's disease. Brain Stimul 8: 224-230 [CrossRef] [Google Scholar] [PubMed]
  26. Marinelli L, Quartarone A, Hallett M, Frazzitta G, Ghilardi MF, et al. (2017) The many facets of motor learning and their relevance for Parkinson's disease. Clin Neurophysiol 128: 1127-1141 [CrossRef] [Google Scholar] [PubMed]
  27. Koganemaru S, Fukuyama H, Mima T (2015) Two is More Than One: How to Combine Brain Stimulation Rehabilitative Training for Functional Recovery? Frontiers in systems neuroscience 9:154 [CrossRef] [Google Scholar] [PubMed]
  28. Franchignoni F, Horak F, Godi M, Nardone A, Giordano A, et al. (2010) Using psychometric techniques to improve the Balance Evaluation Systems Test: the mini-BESTest. J Rehabil Med 42: 323-331 [CrossRef] [Google Scholar] [PubMed]
  29. Bloem BR, Marinus J, Almeida Q, Dibble L, Nieuwboer A, et al. (2016) Measurement instruments to assess posture, gait, and balance in Parkinson's disease: Critique and recommendations. Mov Disord 31: 1342-1355 [CrossRef] [Google Scholar] [PubMed]
  30. Duncan RP, Leddy AL, Earhart GM (2011) Five times sit-to-stand test performance in Parkinson's disease. Arch Phys Med Rehabil 92: 1431-1436 [CrossRef] [Google Scholar] [PubMed]
  31. Steffen T, Seney M (2008) Test-retest reliability and minimal detectable change on balance and ambulation tests, the 36-item short-form health survey, and the unified Parkinson disease rating scale in people with parkinsonism. Phys Ther 88: 733-746 [CrossRef] [Google Scholar] [PubMed]
  32. Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, et al. (2008) Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Mov Disord 23: 2129-2170 [CrossRef] [Google Scholar] [PubMed]
  33. Dal Bello-Haas V, Klassen L, Sheppard MS, Metcalfe A (2011) Psychometric Properties of Activity, Self-Efficacy, and Quality-of-Life Measures in Individuals with Parkinson Disease. Physiother Can 63: 47-57 [CrossRef] [Google Scholar] [PubMed]
  34. Bushnell DM, Martin ML (1999) Quality of life and Parkinson's disease: translation and validation of the US Parkinson's Disease Questionnaire (PDQ-39). Qual Life Res 8: 345-350 [CrossRef] [Google Scholar] [PubMed]
  35. Bashir S, Mizrahi I, Weaver K, Fregni F, Pascual-Leone A, et al. (2010) Assessment and modulation of neural plasticity in rehabilitation with transcranial magnetic stimulation. PM R 2: 253-268 [CrossRef] [Google Scholar] [PubMed]