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International Journal of Clinical Research & Trials Volume 3 (2018), Article ID 3:IJCRT, 03 pages
https://doi.org/10.15344/2456-8007/2018/122
Research Article
Cerebral Vasoreactivity in Parkinson's Disease: A Pilot Study

Giuliano Sette1, Elisabetta Indelicato1,2, Alessandra Fanciulli2, Jacob Shofany3 and Francesco E. Pontieri1,3*

1Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), “Sapienza” University of Rome, Italy
2Department of Neurology, Medical University of Innsbruck, Austria
3Department of Clinical and Behavioral Neurology, IRCCS “Santa Lucia Foundation”, Rome, Italy
Dr. Francesco E. Pontieri, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy; E-mail: fe.pontieri@gmail.com
14 November 2017; 11 January 2018; 13 January 2018
Sette G, Indelicato E, Fanciulli A, Shofany J, Pontieri FE, et al. (2018) Cerebral Vasoreactivity in Parkinson's Disease: A Pilot Study. Int J Clin Res Trials 3: 122. doi: https://doi.org/10.15344/2456-8007/2018/122

References

  1. Velseboer DC, de Hann RJ, Wieling W, Goldstein DS, de Bie RM, et al. (2011) Prevalence of orthostatic hypotension in Parkinson’s disease: a systematic review and meta-analysis. Parkinsonism Relat Disord 17: 724- 729 [CrossRef] [Google Scholar] [PubMed]
  2. Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, et al. (2011) Consensus Statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Autonom Res 21: 69-72 [CrossRef] [Google Scholar] [PubMed]
  3. Fanciulli A, Strano S, Colosimo C, Caltagirone C, Spalletta G, et al. (2013) The potential prognostic role of cardiovascular autonomic failure in α-synucleinopathies. Eur J Neurol 20: 231-235 [CrossRef] [Google Scholar] [PubMed]
  4. Fanciulli A, Goebel G, Ndayisaba JP, et al. (2016) Supine hypertension in Parkinson’s disease and multiple system atrophy. Clin Autonom Res 26: 97-105 [CrossRef] [Google Scholar] [PubMed]
  5. Indelicato E, Fanciulli A, Poewe W, Antonini A, Pontieri FE, et al. (2015) Cerebral autoregulation and white matter lesions in Parkinson´s disease and multiple system atrophy. Parkinsonism Relat Disord 21: 1393-1397 [CrossRef] [Google Scholar] [PubMed]
  6. Bohnen NI, Albin RL (2011) White matter lesions in Parkinson disease. Nat Rev Neurol 7: 229-236 [CrossRef] [Google Scholar] [PubMed]
  7. Camargo CHF, Martins EA, Lange MC, Hoffmann HA, Luciano JJ, et al. (2015) Abnormal cerebrovascular reactivity in patients with Parkinson's disease. Parkinson’s Dis 523041 [CrossRef] [Google Scholar] [PubMed]
  8. Zamani B, Mehrabani M, Fereshtehnejad SM, Rohani M (2011) Evaluation of cerebral vasomotor reactivity in Parkinson´s disease: is there any association with orthostatic hypotension? Clin Neurol Neurosurg 5: 368- 372 [CrossRef] [Google Scholar] [PubMed]
  9. Markus HS, Harrison MJ (1992) Estimation of cerebrovascular reactivity using transcranial doppler, including the use of breath-holding as a vasodilatory stimulus. Stroke 23: 668-673 [CrossRef] [Google Scholar] [PubMed]
  10. Lavi S, Gaitini D, Milloul V, Jacob G (2006) Impaired cerebral CO2 vasoreactivity: association with endothelial dysfunction. Am J Physiol Heart Circ Physiol 291: 1856-1861 [CrossRef] [Google Scholar] [PubMed]
  11. Reinhard M, Schwarzer G, Briel M, Altamura C, Palazzo P et al. (2014) Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease. Neurology 83: 1424-1431 [CrossRef] [Google Scholar] [PubMed]
  12. Gelb DJ, Oliver E, Gilman S (1999) Diagnostic criteria for Parkinson’s disease. Arch Neurol 56: 33-39 [CrossRef] [Google Scholar] [PubMed]
  13. Tomlinson CL, Stowe R, Patel S, Rick C, Gray R, et al. (2010) Systematic review of levodopa dose equivalency reporting in Parkinson’s disease. Mov Disord 15: 2649-2653 [CrossRef] [Google Scholar] [PubMed]