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International Journal of Clinical Pharmacology & Pharmacotherapy Volume 3 (2018), Article ID 3:IJCPP-140, 6 pages
https://doi.org/10.15344/2456-3501/2018/140
Research Article
Clinical Outcomes from Tamoxifen Drug-herb Interactions

Campos Maria Graça1,2*, Mariana Cupido1, Raquel Tavares1 and Raquel Consul1

1Observatory of Drug-Herb Interactions/ Faculty of Pharmacy, University of Coimbra, Health Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal
2Coimbra Chemistry Centre, University of Coimbra, Rua Larga, Coimbra, Portugal
Dr. Campos Maria Graça, Observatory of Drug- Herb Interactions/ Faculty of Pharmacy, University of Coimbra, Health Sciences Campus, Azinhaga de Santa Comba, Coimbra Portugal; E-mail: mgcampos@ff.uc.pt
31 May 2018; 06 August 2018; 08 August 2018
Graça CM, Cupido M, Tavares R, Consul R (2018) Clinical Outcomes from Tamoxifen Drug-herb Interactions. Int J Clin Pharmacol Pharmacother 3: 140. doi: https://doi.org/10.15344/2456-3501/2018/140

References

  1. Hormone Therapy for Breast Cancer [View]
  2. Krämer SD, Testa B (2008) The Biochemistry of Drug Metabolism - An Introduction. Part 6. Inter-Individual Factors Affecting Drug Metabolism. Chem Biodivers 5: 2465-2578 [CrossRef] [Google Scholar] [PubMed]
  3. Goetz MP, Rae JM, Suman VJ, Safgren SL, Ames MM, et al. (2005) Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes. J Clin Oncol 23: 9312-9318 [CrossRef] [Google Scholar] [PubMed]
  4. Knox SK, Ingle JN, Suman VJ, Rae JM, Flockhart DA, et al. (2006) Cytochrome P450 2D6 status predicts breast cancer relapse in women receiving adjuvant tamoxifen. J Clin Oncol 24: 504 [CrossRef] [Google Scholar]
  5. Worsnop RL (1993) Dietary Supplements: Should health products be less tightly regulated?
  6. Commission staff working document (2008) Available scientific information on the use of substances other than vitamins and minerals in food supplements. Council of Europe
  7. PassaraniIlaria (2016) Food Supplements. Challenges & risks for consumers. Bureau EuropéenDes Unions De Consommateurs Aisbl. Der Europäische Verbraucher verband [View]
  8. Consortium on Breast Cancer Pharmacogenomics (2008) A Guide for Breast Cancer Patients and Physicians. Drug-Interactions With Tamoxifen [Google Scholar]
  9. Leclercq G, Jacquot Y (2012) Interactions of isoflavones and other plant derived estrogens with estrogen receptors for prevention and treatment of breast cancer-Considerations concerning related efficacy and safety. J Steroid Biochem Mol Biol 139: 237-244 [CrossRef] [Google Scholar] [PubMed]
  10. Silva AG, Brandão AB, Cacciari RS, Soares WH (2009) Avanços na elucidação dos mecanismos de ação de Cimicifugaracemosa (L.) Nutt. Nos sintomas do climatério. Rev Bras Plantas Med 11: 455-464 [Google Scholar]
  11. Jargin SV (2014) Soy and phytoestrogens: possible side effects. Ger Med Sci 12: 18 [CrossRef] [Google Scholar] [PubMed]
  12. Ghazanfarpour M, Sadeghi R, Latifnejad R, Khadivzadeh T, Khorsand I, et al. (2016) Effects of flaxseed and Hypericumperforatum on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women: A systematic review and meta-analysis. Avicenna J Phytomed 6: 273-283 [Google Scholar] [PubMed]
  13. Hao Q, Wang J, Niu J, Zhao P, Cui Y, et al. (2009) Study on phytoestrogeniclike effects of four kinds of Chinese medicine including Radix Rehmanniae Preparata, Radix Paeoniae Alba, Radix Angelicae Sinensis, Rhizoma Chuanxiong. Zhongguo Zhong Yao Za Zhi 34: 620-624 [Google Scholar] [PubMed]
  14. Campos MG, Costa ML (2012) Possible Risks in Caucasians by Consumption of Isoflavones Extracts Based. In Structure and Function of Food Engineering 9: 205-224 [CrossRef] [Google Scholar]
  15. Antunes MV, Timm TAF, Olivera V, Staudt DE, Gossling G, et al (2015) Influence of CYP2D6 and CYP3A4 phenotypes, drug interactions and vitamin D status on tamoxifen biotransformation. Ther Drug Monit 37: 733- 744 [CrossRef] [Google Scholar] [PubMed]
  16. Tamoxifen Summary of Product Characteristics
  17. Jesus NR, Batista C, Silva CM, Silva TP, Costa ML, et al. (2016) Oncological Patients Under Therapy and Potential Risks Associated to Interactions with Natural Products for Constipation Relieve. Int J Clin Pharmacol Pharmacother 1: 117
  18. Djuv A, Nilsen OG (2012) Aloe vera juice: IC50 and dual mechanistic inhibition of CYP3A4 and CYP2D6. Phytother Res 26:445-451 [CrossRef] [Google Scholar] [PubMed]
  19. Sun DX, Lu JC, Fang ZZ, Zhang YY, Cao YF, et al (2010) Reversible inhibition of three important human liver cytochrome p450 enzymes by tiliroside. Phytother Res 24: 1670-1675 [CrossRef] [Google Scholar] [PubMed]
  20. Jaikang C, Niwatananun K, Narongchai P, Narongchai S, Chaiyasut C, et al. (2011) Inhibitory effect of caffeic acid and its derivatives on human liver cytochrome P450 3A4 activity. Journal of Medicinal Plants Research 5:3530- 3536 [Google Scholar]
  21. Antunes MV, Timm TAF, Olivera V, Staudt DE, Gossling G, et al. (2015) Influence of CYP2D6 and CYP3A4 phenotypes, drug interactions and vitamin D status on tamoxifen biotransformation. Ther Drug Monit 37: 733- 744 [CrossRef] [Google Scholar] [PubMed]
  22. Meijerman I, Beijnem JH, Schellens JH (2006) Herb-Drug Interaction in Oncology: Focus on Mechanisms of Induction. Oncologist 11: 742-752 [CrossRef] [Google Scholar] [PubMed]
  23. Sahib HB, Harchan NAH, AtraqchiSAM, Abbas AA (2010) The Role of Medicinal Herbs in Angiogenesis Related Diseases. International Journal of Pharmacology 6: 616-623 [CrossRef] [Google Scholar]
  24. Tai-Ping F, Yeh JC, Leungc KW, Yued PYK , Wongcd NS (2006) Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci 27: 297-309 [CrossRef] [Google Scholar] [PubMed]
  25. Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, et al. (2005) In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes. Clin Pharmacol Ther 77: 415-426 [CrossRef] [Google Scholar] [PubMed]
  26. Yeung JH, Or PM (2012) Polysaccharide peptides from Coriolus versicolor competitively inhibit model cytochrome P450 enzyme probe substrates metabolism in human liver microsomes. Phytomedicine 19: 457- 463 [CrossRef] [Google Scholar] [PubMed]
  27. Bamba Y, Yun YS, Kunugi A, Inoue H (2011) Compounds isolated from Curcuma aromatic Salisb. inhibit human P450 enzymes. J Nat Med 65: 583- 587 [CrossRef] [Google Scholar] [PubMed]
  28. Chen Y, Liu WH, Chen BL, Fan L, Wang G, et al (2010) Plant Polyphenol Curcumin Significantly Affects CYP1A2 and CYP2A6 Activity in Healthy, Male Chinese Volunteers. Ann Pharmacother 44: 1038-1045 [CrossRef] [Google Scholar] [PubMed]
  29. Scott GN, Elmer GW (2002) Update on natural product-drug interactions. Am J Health-Syst Pharm 59: 339-347 [CrossRef] [Google Scholar] [PubMed]
  30. Hyeong JK , In SK, Shaheed UR, Sang KH, Katsunori N, et al. (2017) Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450- mediated drug metabolism. Bioorg Med Chem Lett 27: 1826-1830 [CrossRef] [Google Scholar] [PubMed]
  31. Park JH, Park GM, Kim JK (2015) Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis. Korean J Physiol Pharmacol 19: 335- 340 [CrossRef] [Google Scholar] [PubMed]
  32. Wanwimolruk S, Phopin K, Prachayasittikul V (2014) Cytochrome P450 enzyme mediated herbal drug interactions (Part 2). EXCLI J 13: 869-896 [Google Scholar] [PubMed]
  33. Sagar S, Yance D, Wong R (2006) Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2. Curr Oncol 13: 99-107 [Google Scholar] [PubMed]
  34. Nishikawa M, Ariyoshi N, Kotani A, Ishii I, Nakamura H, et al. (2004) Effects of continuous ingestion of green tea or grape seed extracts on the pharmacokinetics of midazolam. Drug Metab Pharmacokinet 19: 280-289 [CrossRef] [Google Scholar] [PubMed]
  35. Sagar S, Yance D, Wong R (2006) Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2. Curr Oncol 13: 99-107 [Google Scholar] [PubMed]
  36. He W, Wu JJ, Ning J, Hou J, Xin H, et al. (2015) Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice. Toxicol In Vitro 29: 1569-1576 [CrossRef] [Google Scholar] [PubMed]
  37. Chen S, Yong T, Zhang Y, Su J, Jiao CY, et al. (2017) Anti-tumor and Antiangiogenic Ergosterols from Ganodermalucidum. Front Chem 5: 85 [CrossRef] [Google Scholar] [PubMed]
  38. Goey AK, Meijerman I, Rosing H, Marchetti S, Mergui-Roelvink M, et al. (2014) The Effect of St John's Wort on the Pharmacokinetics of Docetaxel. Clin Pharmacokinet 76: 467-474 [CrossRef] [Google Scholar] [PubMed]
  39. Nowack R (2008) Review Article: Cytochrome P450 enzyme, and transport protein mediated herb-drug interactions in renal transplant patients: Grapefruit juice, St John’s Wort and beyond. Nephrology 13: 337-347 [CrossRef] [Google Scholar] [PubMed]