Use of 99mTc-labelled Anti-TNF Monoclonal Antibodies to Assess Patients Affected by Inflammatory Arthropathies

doi:10.15344/2456-446X/2015/102

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International Journal of Radiology & Medical Imaging Volume 1 (2015), Article ID 1:IJRMI-102, 3 pages
https://doi.org/10.15344/2456-446X/2015/102

Mini Review

Use of ^99mTc-labelled Anti-TNF Monoclonal Antibodies to Assess Patients Affected by Inflammatory Arthropathies

Fulvia Ceccarelli¹, Carlo Perricone¹, Filippo Galli², Guido Valesini¹ and Fabrizio Conti^1*

¹Rheumatology, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161, Roma, Italy
²Nuclear Medicine Unit,Faculty of Medicine and Psychology,Department of Medical-Surgical Sciences and Translational Medicine, "Sapienza" University,Ospedale S. Andrea, Via di Grottarossa 1035; 00189 Rome, Italy

Corresponding Author Details: Dr. Fabrizio Conti, Rheumatology, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155, 00161, Roma, Italy; E-mail: fabrizio.conti@uniroma1.it

Received: 20 March 2015; Accepted: 01 July 2015; Published: 03 July 2015

Citation: Ceccarelli F, Perricone C, Galli F, Valesini G, Conti F (2015) Use of ^99mTc-labelled anti-TNF Monoclonal Antibodies to Assess Patients Affected by Inflammatory Arthropathies. Int J Radiol Med Imag 1: 102. doi: https://doi.org/10.15344/2456-446X/2015/102

Copyright: © 2015 Ceccarelli et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Nuclear medicine techniques have been applied for many years to assess the activity in patients with different inflammatory arthropathies. The recent development of specific radiopharmaceuticals suggested the possibility to use nuclear medicine in order to clarify the disease mechanisms and predict response to treatment. In this review, we aimed at presenting data concerning the use of ^99mTc-labelled anti-TNF monoclonal antibodies. Few studies have been conducted in patients affected by Rheumatoid Arthritis and Spondyloarthropathies, treated for systemic or mono-articular involvement, showing the possible use of this specific scintigraphy.

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