Abstract

Solid tumors discovered at birth or during the first month after delivery are rare. Malignant tumors in neonates represent only 2% of all malignancies in childhood. Some tumors which appear histologically malignant may show benign behavior while apparently benign tumors may be fatal by virtue of their site of origin, which make neonatal tumors difficult diagnostic and therapeutic challenges in neonatal units. Planning diagnostic work-up and therapeutic interventions requires a multidisciplinary approach that involves, feto-maternal, neonatology, radiology, surgery, pathology, hematology, oncology and supportive care services. Here we provide a general overview of the most common malignant tumors seen in the newborn period.