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International Journal of Laboratory Medicine & Research Volume 1 (2015), Article ID 1:IJLMR-102, 3 pages
http://dx.doi.org/10.15344/2455-4006/2015/102
Research Article
Factor V Leiden Mutation and Color of Skin in Arabs

Mehrez M. Jadaon and Ali A. Dashti*

Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Sulaibekhat 90805, Kuwait
Prof. Ali A. Dashti, Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Sulaibekhat 90805, Kuwait; Tel: (00965) 66090302; Fax: (00965) 24633835; E-mail: aad@hsc.edu.kw
10 November 2014; 20 February 2015; 22 February 2015
Jadaon MM, Dashti AA (2015) Factor V Leiden Mutation and Color of Skin in Arabs. Int J Lab Med Res 1: 102. doi: http://dx.doi.org/10.15344/2455-4006/2015/102

References

  1. Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, et al. (1994) Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369: 64-67. View
  2. Dahlbäck B, Carlsson M, Svensson PJ (1993) Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci U S A 90: 1004-1008. View
  3. Ridker PM, Miletich JP, Hennekens CH, Buring JE (1997) Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening. JAMA 277: 1305-1307. View
  4. Faioni EM, Razzari C, Martinelli I, Panzeri D, Franchi F, et al. (1997) Resistance to activated protein C in unselected patients with arterial and venous thrombosis. Am J Hematol 55: 59-64. View
  5. Rees DC, Cox M, Clegg JB (1995) World distribution of factor V Leiden. Lancet 346: 1133-1134. View
  6. Cox MJ, Rees DC, Martinson JJ, Clegg JB (1996) Evidence for a single origin of factor V Leiden. Br J Haematol 92: 1022-1025. View
  7. Simioni P, Prandoni P, Lensing AW, Scudeller A, Sardella C, et al. (1997) The risk of recurrent venous thromboembolism in patients with an Arg506- ->Gln mutation in the gene for factor V (factor V Leiden). N Engl J Med 336: 399-403. View
  8. de Maat MP, Kluft C, Jespersen J, Gram J (1996) World distribution of factor V Leiden mutation. Lancet 347: 58. View
  9. Dzimiri N, Meyer B (1996) World distribution of factor V Leiden. Lancet 347: 481-482. View
  10. Bennett JA, Palmer LJ, Musk AW, Erber WN (2001) Prevalence of factor V Leiden and prothrombin 20210A mutations in indigenous Australians. Thromb Haemost 86: 1592-1593. View
  11. Arruda VR, Annichino-Bizzacchi JM, Costa FF, Reitsma PH (1995) Factor V Leiden (FVQ 506) is common in a Brazilian population. Am J Hematol 49: 242-243. View
  12. Zama T, Murata M, Ono F, Watanabe K, Watanabe R, et al. (1996) Low prevalence of activated protein C resistance and coagulation factor V Arg506 to Gln mutation among Japanese patients with various forms of thrombosis, and normal individuals. Int J Hematol 65: 71-78. View
  13. Pepe G, Rickards O, Vanegas OC, Brunelli T, Gori AM, et al. (1997) Prevalence of factor V Leiden mutation in non-European populations. Thromb Haemost 77: 329-331. View
  14. Ho CH, Chau WK, Hsu HC, Gau JP, Chih CM (1999) Prevalence of factor V Leiden in the Chinese population. Zhonghua Yi Xue Za Zhi (Taipei) 62: 875-878. View
  15. Zivelin A, Griffin JH, Xu X, Pabinger I, Samama M, et al. (1997) A single genetic origin for a common Caucasian risk factor for venous thrombosis. Blood 89: 397-402. View
  16. Jadaon MM, Dashti AA, Lewis HL (2010) High prevalence of activated protein C resistance and factor V Leiden mutation in an Arab population and patients with venous thrombosis in Kuwait. Diagn Mol Pathol 19: 180- 183. View
  17. Rosen E, Renbaum P, Heyd J, Levy-Lahad E (1999) High frequency of factor V Leiden in a population of Israeli Arabs. Thromb Haemost 82: 1768. View
  18. Almawi WY, Tamim H, Kreidy R, Timson G, Rahal E, et al. (2005) A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis. J Thromb Thrombolysis 19: 189-196. View
  19. Eid SS, Shubeilat T (2005) Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR G677A among 594 thrombotic Jordanian patients. Blood Coagul Fibrinolysis 16: 417-421. View
  20. Irani-Hakime N, Tamim H, Elias G, Finan RR, Daccache JL, et al. (2000) High prevalence of factor V mutation (Leiden) in the Eastern Mediterranean. Clin Chem 46: 134-136. View
  21. Taher A, Khalil I, Shamseddine A, El-Ahdab F, Bazarbachi A (2001) High prevalence of Factor V Leiden mutation among healthy individuals and patients with deep venous thrombosis in Lebanon: is the eastern Mediterranean region the area of origin of this mutation? Thromb Haemost 86: 723-724. View
  22. Eid SS, Shubeilat T (2005) Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR G677A among 594 thrombotic Jordanian patients. Blood Coagul Fibrinolysis 16: 417-421. View
  23. El-Karaksy H, El-Koofy N, El-Hawary M, Mostafa A, Aziz M, et al. (2004) Prevalence of factor V Leiden mutation and other hereditary thrombophilic factors in Egyptian children with portal vein thrombosis: results of a singlecenter case-control study. Ann Hematol 83: 712-715. View
  24. Pathare A, Al Kindi S, Al Haddabi H, Dennison D, Bayoumi R, et al. (2006) Hereditary thrombophilia in ethnic Omani patients. Am J Hematol 81: 101- 106. View
  25. Settin A, Dowaidar M, El-Baz R, Abd-Al-Samad A, El-Sayed I, et al. (2008) Frequency of factor V Leiden mutation in Egyptian cases with myocardial infarction. Hematology 13: 170-174. View
  26. Tamim H, Finan RR, Almawi WY (2002) Prevalence of two thrombophilia predisposing mutations: factor V G1691A (R506Q; Leiden) and prothrombin G20210A, among healthy Lebanese. Thromb Haemost 88: 691-692. View
  27. Finan RR, Tamim H, Ameen G, Sharida HE, Rashid M, et al. (2002) Prevalence of factor V G1691A (factor V-Leiden) and prothrombin G20210A gene mutations in a recurrent miscarriage population. Am J Hematol 71: 300-305. View
  28. Eid SS, Rihani G (2004) Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations in 200 healthy Jordanians. Clin Lab Sci 17: 200-202. View
  29. Awidi A, Shannak M, Bseiso A, Kailani MA, Kailani MA, et al. (1999) High prevalence of factor V Leiden in healthy Jordanian Arabs. Thromb Haemost 81: 582-584. View
  30. Almawi WY, Keleshian SH, Borgi L, Fawaz NA, Abboud N, et al. (2005) Varied prevalence of factor V G1691A (Leiden) and prothrombin G20210A single nucleotide polymorphisms among Arabs. J Thromb Thrombolysis 20: 163-168. View
  31. Dashti AA, Jadaon MM, Lewis HL (2010) Factor V Leiden mutation in Arabs in Kuwait by real-time PCR: different values for different Arabs. J Hum Genet 55: 232-235. View
  32. Dashti AA, Jadaon MM, Abdulsamad AM, Dashti MH, Lewis HL (2011) Thrombosis risk in carriers of the factor V Leiden mutation: is it associated with a defined skin color? Pathol Res Pract 207: 671-673. View