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International Journal of Clinical Pharmacology & Pharmacotherapy Volume 4 (2019), Article ID 4:IJCPP-143, 5 pages
https://doi.org/10.15344/2456-3501/2019/143
Research Article
A Study on Quality of Life versus Asthma Control in Mild to Moderate Persistent Asthma Patients Treated at a Secondary Care Hospital in Oman

Azza Darwish AL-Balushi1, Sabin Thomas1*, Dhabya AL Marzooq2

1School of Pharmacy, College of Pharmacy & Nursing, University of Nizwa, Birkat Al Mouz, Nizwa, Sultanate of Oman
2Department of Pharmacy, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman
Dr. Sabin Thomas, School of Pharmacy, College of Pharmacy & Nursing, University of Nizwa, PB-33, PC-616, Birkat Al Mouz, Nizwa, Sultanate of Oman; E-mail: sabin@unizwa.edu.om
11 December 2018; 11 February 2019; 13 February 2019
AL-Balushi AD, Thomas S, AL Marzooq D (2019) A Study on Quality of Life versus Asthma Control in Mild to Moderate Persistent Asthma Patients Treated at a Secondary Care Hospital in Oman. Int J Clin Pharmacol Pharmacother 4: 143.doi: https://doi.org/10.15344/2456-3501/2019/143

Abstract

Background: Regardless of severity, persistent asthma impacts significantly on the health-related quality of life. The increasing prevalence of asthma among the Middle East countries accounts for assessing the level of asthma control and quality of life among suffering asthmatics. The study evaluated the health outcomes of asthmatics who received ambulatory care in the Sultanate of Oman.
Method: A prospective observational study was conducted on 31 mild to moderate persistent asthma patients at a secondary care setup. Patients satisfying study criteria signed informed consent to enter the study. Quality of life was assessed using the JuniperMini-Asthma Quality of Life Questionnaire (Mini- AQLQ) and asthma control using the Asthma Control Test (ACT). Descriptive statistics applied for demographics and data presented in percentages and mean ± standard deviation. Independent sample t-test was performed to the severity subgroups of Mini-AQLQ scores and ACT values. Pearsons correlation was done to establish an association of ACT to AQLQ total score.
Results: Patients enrolled aged 34.16±2.26 years and 74.2% of patients suffered moderate persistent asthma. About 61.3% of patients reported having allergic rhinitis. The moderate persistent asthmatics reported a poor quality of life (3.8±0.81) compared to patients with mild persistent asthma (4.53±0.84). About 58% of patients were having good asthma control with a mean ACT score 22.5±1.64. The activity limitation and environmental stimuli scores of Mini-AQLQ significantly (p<0.05) correlates with the ACT values of patients signifying the factors ignored for better control over asthma among the population.
Conclusion: Moderate persistent asthma patients experienced a poor quality of life and require treatment modifications. Mini-AQLQ is adaptable in the Omani population for QoL evaluation. The activity limitations and environmental stimuli are unavoidable factors to be addressed for the control of asthma among the Omani population to achieve a better quality of life.