International Journal of Clinical Pharmacology & Pharmacotherapy Volume 2 (2017), Article ID 2:IJCPP-132, 7 pages
Research Article
The Effect of Osteopathic Manipulation Therapy (OMT) in Patients with Gastroesophageal Reflux Disease (GERD)

Kjell E. Bjørnæs1, Stig Larsen2, Terje Skauvik3, Øystein Myklebust3, Erik Fosse3 and Ola Reiertsen4

1Nordic Osteopathic Research Institute, Box 23, 9501 Alta, Norway
2Norwegian University of life sciences, Faculty of Veterinary medicineUllevålsveien 72, 0033 Oslo, Norway
3Osteopaths DO, Frisksentret, Moaveien 11, 6018 Ålesund, Norway
4Department of Digestive Surgery, Akershus University Hospital, Sykehusveien 25,1478 Lørenskog, Norway
Kjell E. Bjørnæs, Nordic Osteopathic Research Institute, Box 23, 9501 Alta, Norway; E-mail:
09 October 2017; 13 December 2017; 15 December 2017
Bjørnæs KE, Larsen S, Skauvik T, Myklebust Ø, Fosse E, et al. (2017) The Effect of Osteopathic Manipulation Therapy (OMT) in Patients with Gastroesophageal Reflux Disease (GERD). Int J Clin Pharmacol Pharmacother 2: 132. doi:


Aim: To estimate and compare the effect of osteopathic manipulation therapy (OMT) on gastroesophageal reflux disease (GERD) against a placebo.
Material: The study group consisted of 58 patients who had GERD symptoms for a mean duration of 10.7 years. Twenty-six men and 18 women were administered OMT, and eight men and six women were administered a placebo.
Methods: The study was a randomised double-blinded multicentre trial with a stratified parallel group design. Patients were allocated (3:1) to OMT or placebo by block randomisation. OMT included traction of the cardiac, mobilisation of the diaphragm and thoracic spine, and posture correction once per week. The control group was treated with a non-active laser pen on the epigastric area. The degree and duration of GERD symptoms, provoking factors, and use of antireflux medication were recorded by the patients.
Results: All the GERD symptoms were significantly reduced (p<0.01) 1 week after the last treatment in the OMT group compared to no reduction in the control group. The reductions were significantly in the favour of OMT (P<0.01). Twelve percent of the OMT patients were symptom free, and 75% reported a greater than 50% reduction in symptoms. “Acid taste in the mouth” and “heartburn” was reduced by 81%. The median time of pain relief was significantly reduced in the OMTgroup compared with that in the control group (p<0.01).
Conclusion: OMT had a significant effect on the GERD symptoms and might be an alternative treatment for reflux oesophagitis.