Profile

New User

New to Graphy Publications? Create an account to get started today.

Registered Users

Have an account? Sign in now.

How to Cite | Author Information | Publication History
International Journal of Clinical Pharmacology & Pharmacotherapy Volume 2 (2017), Article ID 2:IJCPP-124, 2 pages
https://doi.org/10.15344/2456-3501/2017/124
Commentary
Coffee Consumption-A Genetic Approach

Roseane M Santos1,* and Lima DRA2

1Department of Pharmaceutical Sciences, South University School of Pharmacy, 709 Mall Boulevard, Room 341, Savannah, GA 31419, USA
2Instituto of Neurology, Federal University of Rio de Janeiro, Brazil
Prof. Roseane M. Santos, Department of Pharmaceutical Sciences, South University School of Pharmacy, 709 Mall Boulevard, Room 341, Savannah, GA 31419, Tel: 912-201-8131 USA; E-mail: rsantos@southuniversity.edu
29 December 2016; 28 January 2017; 31 January 2017
Santos RM, Lima DRA (2016) Coffee Consumption-A Genetic Approach. Int J Clin Pharmacol Pharmacother 2: 124. doi: https://doi.org/10.15344/2456-3501/2017/124
© 2017 Santos et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

References

  1. Cornelis MC, Monda KL, Yu K, Paynter N, Azzato EM, et al. (2011) Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. PLoS genetics 7: e1002033 [CrossRef] [Google Scholar] [PubMed]
  2. Josse AR, Da Costa LA, Campos H, El-Sohemy A (2012) Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption. Am J Clin Nutr 96: 665-671 [CrossRef] [Google Scholar] [PubMed]
  3. Rasmussen BB, Brix TH, Kyvik KO, Brosen K (2002) The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors. Pharmacogenetics 12: 473-478 [CrossRef] [Google Scholar] [PubMed]
  4. Cornelis MC, El-Sohemy A, Campos H (2004) Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction. J Med Genet 41: 758- 762. [CrossRef] [Google Scholar] [PubMed]
  5. Cornelis MC, El-Sohemy A, Campos H (2007) Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption. Am J Clin Nutr 86: 240-244 [CrossRef] [Google Scholar] [PubMed]
  6. Santos RM, Cotta K, Jiang S, Lima DRA (2014) Does CYP1A2 Genotype influence coffee consumption? Austin J Pharmacol Ther 3: 1065 [Google Scholar]
  7. Sachse C, Brockmoller J, Bauer S, Roots I (1999) Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. British journal of clinical pharmacology 47: 445-449 [CrossRef] [Google Scholar] [PubMed]
  8. Han XM, Ou-Yang DS, Lu PX, Jiang CH, Shu Y, et al. (2001) Plasma caffeine metabolite ratio (17X/137X) in vivo associated with G-2964A and C734A polymorphisms of human CYP1A2. Pharmacogenetics 11: 429-435 [CrossRef] [Google Scholar] [PubMed]
  9. Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, et al. (2012) Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Mol Psychiatry 17:1116-1129 [CrossRef] [Google Scholar] [PubMed]
  10. Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, et al. (2014) Genomewide meta-analysis identifies six novel loci associated with habitual coffee consumption. Mol Psychiatry 20: 647-656 [CrossRef] [Google Scholar] [PubMed]
  11. Jia H, Aw W, Egashira K, Takahashi S, Aoyama S, et al. (2014) Coffee intake mitigated inflammation and obesity-induced insulin resistance in skeletal muscle of high-fat diet-induced obese mice. Genes Nutr 9: 389 [CrossRef] [Google Scholar] [PubMed]
  12. McMahon G, Taylor AE, Davey Smith G, Munafò MR (2014) Phenotype refinement strengthens the association of AHR and CYP1A1 genotype with caffeine consumption. PLoS One 9: e103448 [CrossRef] [Google Scholar] [PubMed]
  13. Palatini P, Ceolotto G, Ragazzo F, Dorigatti F, Saladini F, et al. (2009) CYP1A2 genotype modifies the association between coffee intake and the risk of hypertension. J Hypertens 27: 1594-1601 [CrossRef] [Google Scholar] [PubMed]
  14. Santos RM, Lima DR (2016) Coffee consumption, obesity and type 2 diabetes: a mini-review. Eur J Nutr 55: 1345-1358 [CrossRef] [Google Scholar] [PubMed]
  15. Yang A, Palmer AA, de Wit H (2010) Genetics of caffeine consumption and responses to caffeine. Psychopharmacology (Berl) 211: 245-257 [CrossRef] [Google Scholar] [PubMed]
  16. Sulem P, Gudbjartsson DF, Geller F, Prokopenko I, Feenstra B, et al. (2011) Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. Hum Mol Genet 20 :2071-2077 [CrossRef] [Google Scholar] [PubMed]
Best viewed in Mozilla Firefox, Google Chrome, Safari, Above IE 9.0 version
Privacy Policy | Copyright & Permissions
Copyright © 2013-2024 Graphy Publications, All Rights Reserved.