Profile
International Journal of Clinical Case Studies Volume 1 (2015), Article ID 1:IJCCS-101, 3 pages
http://dx.doi.org/10.15344/2455-2356/2015/101
Case Report
Should We Consider Bilirubin When Dosing Troponin in Newborns? Case Report

Valentina Giacchi1*, Carmine Mattia2, Pasqua Betta2 and Pietro Sciacca3

1Department of Pediatrics, AOU Policlinico-Vittorio Emanuele, via Santa Sofia 78 – 95123, Catania, Italy
2NICU, AOU Policlinico-Vittorio Emanuele, via Santa Sofia 78 – 95123, Catania, Italy
3Pediatric Cardiology, AOU Policlinico-Vittorio Emanuele, via Santa Sofia 78 – 95123, Catania, Italy
Dr. Valentina Giacchi, Department of Pediatrics, AOU Policlinico-Vittorio Emanuele, via Santa Sofia 78-95123, Catania, Tel: 00393334126158; Fax: 0953782417, Italy; E-mail: valentina.giacchi@yahoo.it
27 February 2015; 20 March 2015; 22 March 2015
Giacchi V, Mattia C, Betta P, Sciacca P (2014) Should we consider bilirubin when dosing troponin in newborns? Case Report. Int J Clin Case Stud 1: 101. doi: http://dx.doi.org/10.15344/2455-2356/2015/101

Abstract

Background: Troponin is a protein of the troponin-tropomyosin complex in myocardium and it is considered an highly sensitive marker of myocardial necrosis both in adults and newborns with perinatal asphyxia. Some studies assume that high troponin levels in adults without signs of myocardial necrosis could be conditioned by some factors, such as hemolysis, turbidity, and hyperbilirubinemia.
Case presentation: We report a case of a term female newborn of Caucasian race, with high troponin levels in absence of neonatal asphyxia and without clinical or instrumental signs of myocardial ischaemia.
Conclusion: Hyperbilirubinemia might be a factor that could interfere with assessment of sieric troponin T. This might suggest that levels of troponin T should be trusted only when they are associated with signs of other conditions suggesting heart damage or respiratory distress.