Table 10: Clinical characteristics of the patients affecting distant recurrence in univariate and multivariate analysis (Cox regression model).
CI*; confidence interval, NR†; not reached at median value, NA‡; not assessed, NSCLC§; non-small cell lung cancer, KPS☐; Karnofsky Performance Scale.
| Factor | median | median survival (month) | univariate analysis (p value) | Hazard ratio (95% CI*) | multivariate analysis (p value) | Hazard ratio (95% CI) |
| Gender | male | NR† | 0.419 | 1.36 (0.64, 2.87) | NA‡ | |
| female | NR |
| Age | ≥ 65 years | NR | 0.397 | 1.46 (0.60, 3.56) | NA | |
| < 65 years | NR |
| Pathology | NSCLC§ | NR | 0.734 | 1.14 (0.54, 2.40) | NA | |
| non-NSCLC | NR |
| Extracranial metastasis | presence | NR | 0.083 | 1.89 (0.91, 3.62) | NA | |
| absence | NR |
| Status of cancer | under-control | NR | 0.005 | 2.61 (1.29, 5.26) | 0.023 | 2.89 (1.16, 7.23) |
| out-of-control | 11.4 |
| KPS☐ score | ≥ 70 | NR | 0.034 | 2.70 (1.04, 7.03) | 0.863 | 1.20 (0.15, 9.94) |
| < 70 | NR |
| Postoperative radiotherapy | performed | NR | 0.278 | 1.55 (0.70, 3.46) | 0.383 | 1.58 (0.57, 4.38) |
| not performed | 11.6 |