Figure 2: Rotational thromboelastometry (ROTEM) assays after administration of tranexamic acid and transfusion of cryoprecipitate.
INTEM, EXTEM, APTEM after administration of tranexamic acid (2g) and transfusion of cryoprecipitate (8 units) showed prolonged and not reached to normal range, but fairly restored of ROTEM parameters compared with post-CPB status. CFT in INTEM and EXTEM showed intensely prolonged value of 201 s, 219 s (reference values; 30–110 s and 34–159 s, respectively), but CFT in APTEM restored to normal value of 95 s (reference values; 34–159 s). α-angle in INTEM, EXTEM, APTEM showed still decreased value of 57°, 52°, 48° (reference values; 70–83°, 63–83° and 63–83°, respectively). MCF in FIBTEM showed normal value of 7 mm (reference value >7 mm).
TA: after administering tranexamic acid (2g) and cryoprecipitate (8 units);α-angle: tangent of the slope between 2 and 20 mm, CFT: clot formation time; A10 and A20: amplitudes 10 min and 20 min after the start of the assay; MCF: maximum clot firmness; CLI30 and CLI45: clot lysis indices (% of clot strength) remaining 30min and 45 min after clotting time.
INTEM, EXTEM, APTEM after administration of tranexamic acid (2g) and transfusion of cryoprecipitate (8 units) showed prolonged and not reached to normal range, but fairly restored of ROTEM parameters compared with post-CPB status. CFT in INTEM and EXTEM showed intensely prolonged value of 201 s, 219 s (reference values; 30–110 s and 34–159 s, respectively), but CFT in APTEM restored to normal value of 95 s (reference values; 34–159 s). α-angle in INTEM, EXTEM, APTEM showed still decreased value of 57°, 52°, 48° (reference values; 70–83°, 63–83° and 63–83°, respectively). MCF in FIBTEM showed normal value of 7 mm (reference value >7 mm).
TA: after administering tranexamic acid (2g) and cryoprecipitate (8 units);α-angle: tangent of the slope between 2 and 20 mm, CFT: clot formation time; A10 and A20: amplitudes 10 min and 20 min after the start of the assay; MCF: maximum clot firmness; CLI30 and CLI45: clot lysis indices (% of clot strength) remaining 30min and 45 min after clotting time.
