Table 3: Stroke occurrence during NOACs.
DA: Dabigatran, RI: Rivaroxaban, AP: Apixaban, Type of stroke:- CE: Cardioembolic Stroke, AT: Atherothrombotic Brain Infarction, TIA: Transient Ischemic Attack, CH: Cerebral Hemorrhage
Case | Age | Initial dose of NOACs | Prevention type | Interval of recurrence | Stroke type | Possible reason of recurrence | Secondary dose of NOACs | BW (kg) | Ccr (ml/min) |
1 | 67 | DA 300mg | 2nd | 510 | CE | Poor adherence | DA 300mg | 64 | 68 |
2 | 71 | DA 220mg | 2nd | 85 | AT | Low dose | DA 300mg | 62 | 117 |
3 | 67 | RI 15mg | 1st | 91 | CE | Post CABG | DA 300mg | 66 | 103 |
4 | 86 | RI 10mg | 2nd | 385 | CE | | RI 10mg | 63 | 72 |
5 | 74 | RI 10mg | 1st | 730 | CE | History of CH and stomach cancer | DA 220mg | 50 | 38 |
6 | 89 | RI 10mg | 2nd | 160 | AT | | AP 5mg | 42 | 120 |
7 | 72 | RI 15mg | 2nd | 160 | CE | | AP 10mg | 55 | 86 |
8 | 80 | AP 5mg | 1st | 130 | TIA | | AP 5mg | 75 | 62 |
9 | 92 | DA 220mg | 2nd | 50 | CE | High age | AP 5mg | 56 | 53 |
10 | 78 | DA 220mg | 2nd | 300 | CH | Near the old lacune | RI 10mg | 52 | 78 |