Figure 4: Influence of chondroitin sulfate (CS) on periostin mRNA expression after IL-13 stimulation in vitro. Human synoviocytes from an OA patient (HFLS-OA) at 1 x 105 cells/ml were cultured with 10.0 ng/ml IL-13 for 24 h in the presence of various concentrations of CS. Periostin mRNA expression was measured by real time RT-PCR and the data expressed are the mean relative quantity (RQ) ± SE of triplicate cultures. Med. alone: Medium alone. One representative experiment of two.

figure 4