Figure 2: Influence of chondroitin sulfate (CS) on periostin production from HFLS-OA after IL-13 stimulation in vitro. Human synoviocytes from an OA patient (HFLS-OA) at 1 x 105 cells/ml were cultured with 10.0 ng/ml IL-13 for 48 h in the presence of various concentrations of CS. Periostin concentration in culture supernatants was measured by ELISA and the results were expressed as the mean ng/ml ± SE of triplicate cultures. Med. alone: Medium alone. One representative experiment of two.

figure 2