Table 2: In vitro cumulative amounts and penetrated behavior of AA2G across murine skin with control and microemulsion or commercial emulsion producttreated for 12 h.
a None: None detected to calculated. b Enhancement ratio (ER) = ratio of AA2G of the microemulsion formulation to AA2G in control solution. Data represent the mean ± SD (n = 4).
| Formulation | Cumulative amounts (μg/cm2) | Penetration model | Corrlation coefficient (r) | Flux (μg/cm2/h) | Enhancement ratio (ER) |
| Control | 6.56 ± 7.30 | Nonea | Nonea | 0.44 | -- |
| AA2G microemulsion | 560 ± 327 | Zero | 0.9683 | 46.89 | 100.72 |
| Commercial emulsion produc | 101 ± 42 | Zero | 0.9932 | 8.33 | 18.17 |