Table 1: Influence of Various Conditions on the Permeation of HA4 through Hairless Mice Skin.
Conditions Cumulative amount of HA4 (μg/cm2) Flux (μg/cm2/h) × 10-6 P(cm/s)
Passive Full-thickness skin 0.3±0.1 0.2±0.1 0.01±0.005
Passive Stripped skin 1384.3±32.8 418.0±30.6 23.2±1.7
EP 100 V, 10 ms,50 times 2.3±0.9 0.7±0.3 0.04±0.02
Anodal IP 0.1 mA/cm2 2.0±0.1 0.2±0.1 0.01±0.007
Cathodal IP 0.1 mA/cm2 2310.7±703.1 656.2±197.5 36.5±11.0
Cathodal IP 0.05 mA/cm2 797.9±79.0 236.7±29.8 13.2±1.7