Table 6: Mitochondria respiratory capacity in hearts of non-diabetic, STZ-diabetic and STZ-diabetic rats treated with spent hop extract.
Data are given as mean±SD, n=9-20 animals
Statistical significance, estimated by means of the Kruskal-Wallis test and the post-hoc pairwise multiple comparison Conover-Inman test, is given for:
State 2: In all animal groups: 1 month vs. 5 months and 2.5 months vs. 5 months, P< 0.001;
State 3: In non-diabetic rats: 1 month vs. 5 months, P< 0.001 and 1 month vs. 2.5 months, P< 0.01;
In STZ-diabetic rats: 1 month vs 5 months and 2.5 months vs. 5 months, P< 0.01;
In STZ-diabetic rats + spent hop extract: 1 month vs 5 months, P< 0.05;
State 4: In non-diabetic rats: 1 month vs 5 months and 2.5 months vs. 5 months, P< 0.001;
In STZ-diabetic rats: 1 month vs. 5 months and 2.5 months vs. 5 months, P< 0.001;
In STZ-diabetic rats + spent hop extract: 1 month vs. 5 months and 2.5 months vs. 5 months; P< 0.001;
State E: In all animal groups: 1 month vs. 5 months, P< 0.001; 2.5 months vs. 5 months, P< 0.001.
For experimental and statistical details see ‘Materials and methods’.