Table 3: Effect of spent hop extract on body weight changes in healthy (non-diabetic) rats and STZ-induced diabetic rats. Data are given as mean ± SD, n=9-20 animals.
a Statistical significance vs. non-diabetic rats, estimated with ANOVA for repeated measures or Friedman’s test (depending on the conforming of assumptions) and the post-hoc multiple comparisons tests; P< 0.05.
b Statistical significance vs. non-diabetic rats, estimated with ANOVA for repeated measures or Friedman’s test (depending on the conforming of assumptions) and the post-hoc multiple comparisons tests; P< 0.01.
c Statistical significance vs. non-diabetic rats, estimated with ANOVA for repeated measures or Friedman’s test (depending on the conforming of assumptions) and the post-hoc multiple comparisons tests; P< 0.001.
For more experimental and statistical details see ‘Materials and methods’.
| Week 0 | Week 1 | Week 2 | Week 3 | Week 4 | Week 6 | Week 8 | Week 10 | Week 12 | Week 14 | Week 16 | Week 18 | Week 20 | Week 22 |
non-diabetic rats n=20 | 271±34 | 272±35 | 276±23 | 282±37 | 287±39 | 290±60 | 297±33 | 304±44 | 310±38 | 336±41 | 347±18 | 357±50 | 367±53 | 370±48 |
STZ-diabetic rats n=9-18 | 306±35 | 278±36 | 269±36 | 261±40 | 253±37b | 253±42a | 253±48b | 259±54b | 260±58b | 255±56b | 243±71c | 229±88c | 243±87b | 251±84c |
STZ-diabetic rats with extract n=9-18 | 286±36 | 254±28 | 248±27b | 240±28c | 235±27c | 225±29c | 228±29c | 225±35c | 229±38c | 209±41c | 203±49c | 191±36c | 200±37c | 213±42c |