In-vitro and In-vivo Evaluation of Niosomal Gel Containing Aceclofenac for Sustained Drug Delivery : Table 4

Table 4: In-vitro skin permeation parameters of aceclofenac incorporated in different niosomal and non- niosomal gel formulations.
(Mean ± SD, n = 3)

Niosomes formulation in HPMC (3%w/w)	Permeation parameters
Niosomes formulation in HPMC (3%w/w)	J_ss (mg.cm^-2.hr^-1)	P_app×10² (cm.hr^-1)	Drug permeated after 6 h (mg.cm^-2)
N-2 niosomal gel	0.075 ± 0.011	1.43 ± 0.10	0.449 ± 0.0202
N-8 niosomal gel	0.046 ± 0.012	0.88 ± 0.04	0.250 ± 0.0132
Plain gel	0.0201± 0.010	0.39 ± 0.08	0.120 ± 0.0218