| Antibiotic agent | Pediatric intravenous (a) | Infusion time (minutes) | Timing of first | Intraoperative redosing for normal renal function |
| Ampicillin/Sulbactam | DOSE DULT DOSE50 mg/kg (1.5 ‐ 3 gm) | 30 | DOSE Begin 60 min or less before | Every 3 hrs |
| Cefazolin | 25 mg/kg (max 1 gm; if greater than 80 kg, use 2 gm) | 30 | incision Begin 60 min or less before incision | Every 4 hrs |
| Cefoxitin | 40 mg/kg (1‐2 gm) | 30 | Begin 60 min or less before | Every 3 hrs |
| Cefepime | 50mg/kg (1‐2 gm) | 30 | incision Begin 60 min or less before | Every 4 hrs |
| Clindamycin | 10 mg/kg (600‐900 mg) | 30 | incision Begin 60 min or less before | Every 6 hrs |
| Gentamicin | 2.5 mg/kg (120 mg if > 80 kg) | 30 | incision Begin 60 min or less before | Every 8 hrs |
| Metronidazole | 10 mg/kg (500 mg) | 30 | incision Begin 60 min or less before | Every 6 hrs |
| Vancomycin | 15 mg/kg (1 gm if > 50 kg) | 60 | incision Begin 60 to 120 min before incision | Every 12 hrs |