Table 4: Pharmacokinetic parameters of LORATADINE following administration of single oral dose of Loratadine 10mg Oral Disintegrated Tablets (Test product) to 24 Volunteers.

Test
Subject	Tmax	Cmax	AUClast	AUCINF	Lambda_z	t1/2	MRTINF
A	1.5	1.3696	16.3635	19.9672	0.02779	24.9397	42.7288
B	0.5	3.14745	17.0303	20.5191	0.02994	23.1525	37.886
C	0.75	3.1156	15.73	19.0808	0.02906	23.8526	38.3215
D	1	3.12827	31.1266	33.1376	0.0411	16.8635	26.6466
E	0.75	8.66104	58.1602	67.5178	0.03641	19.037	32.1573
F	0.75	7.21098	56.5941	63.4714	0.02996	23.135	32.504
G	2	3.07894	31.5977	37.9853	0.0279	24.8443	39.8116
H	0.75	6.2269	43.4588	53.1368	0.03427	20.2268	37.4979
I	1	6.96263	34.8732	39.931	0.03873	17.8987	29.9915
J	1	6.86389	64.8857	73.267	0.03054	22.6941	33.2603
K	1.5	3.98689	37.3706	45.3272	0.03035	22.8413	37.5294
L	0.5	7.82417	65.3198	70.8808	0.03752	18.4723	27.5323
M	1	5.8808	33.1465	36.8415	0.04294	16.1412	26.0765
N	4	6.47711	77.1714	84.5555	0.03284	21.1064	26.7005
O	1	6.77925	77.3203	78.7683	0.05164	13.4228	20.7299
P	1.5	8.74915	98.9943	99.9767	0.05751	12.0527	19.5202
Q	2.5	6.76089	50.512	55.7743	0.03345	20.722	28.7109
R	0.5	4.08388	39.1155	43.7087	0.03189	21.7389	32.9819
S	0.333	5.8827	31.766	36.5155	0.03418	20.2787	33.1579
T	1.5	7.868	62.8452	73.5363	0.0326	21.2613	32.4357
U	2.5	4.579	59.569	64.8248	0.03557	19.4863	26.8492
V	0.333	6.81588	77.3222	82.101	0.04289	16.1595	22.5506
W	1	6.80975	60.6873	66.0357	0.03579	19.3665	26.9329
X	2.5	7.45377	33.9627	37.047	0.04021	17.2386	22.7106
Mean	1.27775	5.82152	48.9551	54.3295	0.03605	19.8722	30.6343
SD	0.87943	2.01278	21.9226	22.3423	0.0073	3.39929	6.28431
CV%	68.8268	34.5748	44.781	41.1237	20.2404	17.1058	20.514
Min	0.333	1.3696	15.73	19.0808	0.02779	12.0527	19.5202
Max	4	8.74915	98.9943	99.9767	0.05751	24.9397	42.7288
Median	1	6.619	46.9854	54.4556	0.03422	20.2527	31.0744