Table 1: Pharmacokinetic parameters for Loratadine oral disintergrated tablets of Test and Reference Products.
Pharmacokinetic Parameter Treatment (Mean ± SD)
Test product Reference product
Cmax (ng/ml) 5.8215±2.0128 5.3907±2.0484
Tmax (hr) 1.2778±0.8794 1.4236±0.8098
AUC0-t (ng. hr/ml) 48.9551±21.9226 46.2835±20.6650
AUC0-inf (ng. hr/ml) 54.3295±22.3423 51.3693±22.1563
Ke (hr-1) 0.0360±0.0073 0.0349±0.0061
t (1/2)e (hr) 19.8722±3.3993 20.5016±3.8831
MRT 30.6343±6.2843 29.6545±7.1982