Table 2: Baseline demographics and patient characteristics with 48 h survival.
Significant variables presented in bold.
OSI: oxygen saturation index; CMV: conventional mechanical ventilation, iNO: inhaled nitric oxide; NMB: neuromuscular blocking agent. Data are presented as either a number and percentage or median and interquartile range (IQR).
| | 48 h Survival | |
| Variables | | Survivors n= 170 | Non-survivors n= 37 | P-values |
| Age (month) | 12 (4, 48) | 12 (4, 48) | 11 (3, 43) | 0.85 |
| Weight (kg) | 7.4 (4.1, 12.2) | 7.7 (4.2, 12) | 6 (3.4, 13) | 0.53 |
| Height (cm) | 65 (53, 92) | 67 (54, 91.5) | 60 (51.8, 103) | 0.80 |
| Male | 109 (52.7%) | 86 (50.6%) | 23 (62.2%) | 0.21 |
| OSI Pre-HFOV | 17.8 (14.3, 22) | 18 (14.4, 22.1) | 17.5 (6, 33.3) | 0.63 |
| CMV days pre HFOV | 1.25 (0.5, 6) | 2 (1, 6) | 1 (0.3, 5.5) | 0.046 |
| pH pre-HFOV | 7.18 (7.06, 7.28) | 7.21 (7.10, 7.31) | 6.99 (6.85, 7.20) | < 0.001 |
| PCO2 pre-HFOV | 69 (54, 93) | 69 (54, 95.3) | 68 (50.1, 91) | 0.77 |
| Vasopressor index pre-HFOV | (5, 50) | 0 (0, 21.3) | 70 (10, 190) | < 0.001 |
| Sepsis (associated diagnosis) | 85 (41%) | 59 (34.7%) | 26 (70.3%) | < 0.001 |
| Underlying chronic illness | 181 (87.4%) | 146 (85.9%) | 35 (94.6%) | 0.18 |
| iNO use | 51 (24.6%) | 46 (27.1%) | 5 (13.5%) | 0.095 |
| NMB agent use | 113 (54.6%) | 104 (61.2%) | 9 (24.3%) | < 0.001 |
| Hypotension Pre-HFOV | 40 (19.3%) | 27 (15.9%) | 13 (35.1%) | 0.011 |
| Hypotension anytime during the first 48 hrs of HFOV | 75 (36.4%) | 48 (28.2%) | 27 (75.0%) | < 0.001 |