Table 1: Statistically comparison of follow-up MMSE <26 for the examined bio-parameters. table shows statistically comparisons of follow-up mmse<26 defined as a clear pathologic value and compared with baseline biomarkers 49 patients. categories shown in upper row statistical evaluation column first from left. sixth left values csf (total-tau, phospho-tau, amyloid β-42) combined.
MMSE<26 Follow-up Vigilance-index EEG-frequency Amyloid β-42 total-Tau phospho-Tau Csf pathology
sensitivity 1.0 1.0 1.0 1.0 1.0 1.0
specificity 0.87 0.34 0.35 0.39 0.32 0.28
PPV 0.95 0.31 0.33 0.44 0.22 0.08
NPV 1.0 1.0 1.0 1.0 1.0 1.0