Table 2: Frequencies of low and high values of UV induced unscheduled DNA repair capacity (UDS, relative units) and frequencies of low and high inducibilities of apoptosis (Apo,%), mean values of chromosomal aberrations (CA,%±SE) and sister chromatid exchanges (SCE, 1/mitoses ±SE) in peripheral lymphocytes among controls and health personnel exposed to anesthetics.
Groups | No. of cases | UDS <4 | UDS >9 | Apo <3 | Apo >7 | CA % | SCE 1/mitoses |
Controls | 137 | 23.1 | 12.7 | 8.8 | 28.5 | 1.60 ± 0.13 | 6.25 ± 0.08 |
Controls-nonsmokers | 88 | 20.0 | 10.6 | 10.2 | 30.7 | 1.62 ± 0.16 | 6.10 ± 0.09 |
Controls-smokers | 49 | 28.6 | 16.3 | 6.1 | 24.5 | 1.56 ± 0.22 | 6.53 ± 0.14* |
Exposed-all | 128 | 30.7 | 5.7 | 21.5 | 24.0 | 1.56 ± 0.15 | 6.37 ± 0.08 |
Halothane | 73 | 31.0 | 7.0 | 15.1 | 27.4 | 1.52 ± 0.18 | 6.35 ± 0.10 |
Halothane -nonsmokers | 39 | 23.7 | 5.3 | 5.3 | 42.1 | 1.72 ± 0.26 | 6.07 ± 0.10 |
Halothane -smokers | 34 | 39.4 | 9.1 | 26.4 | 11.8 | 1.28 ± 0.25 | 6.67 ± 0.18* |
Non-Halothane | 55 | 30.2 | 3.8 | 30.6 | 18.4 | 1.63 ± 0.26 | 6.41 ± 0.14 |
Non-Halothane -nonsmokers | 29 | 32.1 | 3.6 | 33.3 | 22.2 | 1.62 ± 0.31 | 6.39 ± 0.14 |
Non-Halothane -smokers | 26 | 28.0 | 4.0 | 27.3 | 13.6 | 1.64 ± 0.45 | 6.43 ± 0.26 |