Table 1: Demographic and clinicopathological variables by stage.
Variable | Stage IIA (n=50) | Stage IIA1 (n=35) | Stage IIA2 (n=15) | P |
Mean age in years (range) | 55.9 (35-84) | 57.5 (35-84) | 52.1 (37-67) | 0.12 |
Race | Chinese | 45 (90%) | 32 (91.4%) | 13 (86.7%) | 0.63 |
Malay | 5 (10%) | 3 (8.6%) | 2 (13.3%) |
Histology | Squamous | 40 (80%) | 29 (82.9%) | 11 (73.3) | 0.149 |
Adenocarcinoma | 6 (12%) | 5 (8.6%) | 1 (6.7%) |
Adenosquamous | 4 (8%) | 1 (2.9%) | 3 (20%) |
Tumour grade | Grade 1 | 3 (6%) | 1 (2.8%) | 2 (13.3%) | 0.437 |
Grade 2 | 21 (42%) | 14 (40%) | 7 (46.7%) |
Grade 3 | 25 (50%) | 19 (54.3%) | 6 (40%) |
Ungrade | 1 (2%) | 1 (2.9%) | 0 (0%) |
Tumour Size | <2cm | 8 (16%) | 8 (22.9%) | 0 (0%) | <0.001 |
2-4cm | 28 (56%) | 27 (77.1%) | 1 (6.7%) |
4-6cm | 11 (22%) | 0 (0%) | 11 (73.3%) |
>6cm | 3 (6%) | 0 (0%) | 3 (20%) |
Treatment | Radical surgery | 23 (46%) | 16 (45.7%) | 7 (46.7%) | 0.50 |
Primary RT | 27 (54%) | 19 (54.3%) | 8 (53.3%) |
Adjuvant RT | Yes | 22 (95.7%) | 15 (93.8%) | 7 (100%) | 1.0 |
No | 1 (4.3%) | 1 (6.3%) | 0 |
Surgery + Adjuvant treatment | RT alone | 5 (22.7%) | 3 (20%) | 2 (28.6%) | 0.655 |
ChemoRT | 17 (77.3) | 12(80%) | 5 (71.4%) |
Primary RT | RT alone | 16 (59.3%) | 15 (78.9%) | 1 (12.5%) | 0.001 |
ChemoRT | 11 (40.7%) | 4 (21.1%) | 7 (87.5%) |