| Indication of prenatal invasive procedures with normal fetal karyotype | AC (n=437) | CVS (n=164) | Total (n=601) | 
| Suspicious first trimester screening | 99 | 90 | 189 | 
| Increased nuchal translucency | 11 | 25 | 36 | 
| Suspicious biochemistry | 74 | 41 | 115 | 
| Combined elevated risk | 14 | 24 | 38 | 
| Maternal age | 209 | 33 | 242 | 
| Suspicious genetic history | 41 | 36 | 77 | 
| Suspicious ultrasound findings | 74 | 5 | 79 | 
| Other indications (request, infections, etc.) | 20 | 0 | 20 | 
| * Total number of indications larger than total population due to double indication | |||