Prenatal Invasive Fetal Karyotyping in the Era of First Trimester Screening and Noninvasive Prenatal Testing (NIPT) : Table 1

Table 1: Indications of prenatal invasive procedures for fetal karyotyping according to AC and CVS.

Indication of prenatal invasive procedures for fetal karyotyping	AC (n=500)	CVS (n=224)	Total (n=724)
Suspicious first trimester screening	120	145	265
Increased nuchal translucency	19	36	55
Suspicious biochemistry	79	46	125
Combined elevated risk	22	63	85
Maternal age	223	33	256
Suspicious genetic history	50	41	91
Suspicious ultrasound findings	95	18	113
Other indications (request, infections, etc.)	23	0	23
* Total number of indications larger than total population due to double indication