Table 1: HMM for CpG islands.
A C G T
0 0 0 0 0
A+ 1 0 0 0
C+ 0 1 0 0
G+ 0 0 1 0
T+ 0 0 0 1
A- 1 0 0 0
C- 0 1 0 0
G- 0 0 1 0
T- 0 0 0 1