| | Aspirin | Second antiplatelet | Statins | Anticoagulation | Valvular surgery | |
1. | 1997, Nighoghossianet al. [5] | LMCA | | | | ✓ | |
2. | 1997, Nighoghossian et al. [5] | LMCA | | | | | ✓ |
3. | 1997, Nighoghossianet al. [5] | LMCA | | | | ✓ | ✓, after recurrent stroke |
4. | 1999, Vorgos et al. [6] | RMCA | | | | | |
5. | 2003, Aggarwal et al. [7] | RMCA | | | | | ✓, after recurrent stroke |
6. | 2006, Siles Rubio et al. [8] | LMCA | ✓ | | | | |
7. | 2007, Aziz et al. [9] | LMCA | | | | | ✓ |
8. | 2007, Wolf et al. [10] | LMCA | ✓ | | | | |
9. | 2010, Kalavakunta et al. [11] | Bilateral B/L cerebral hemispheres | | | | ✓ | |
10. | 2011, Raju et al. [12] | Right posterior circulation | ✓ | | | | |
11. | 2011, Manolakis et al. [13] | Right frontal and right cerebellar | | | | ✓ | ✓ |
12. | 2012, Liu et al. [14] | Left cerebellar hemisphere | ✓ | | | | |
13. | 2012, Liu et al. [14] | Corpus Callosum, right Temporal-Parietal lobe | | | | | ✓ |
14. | 2013, Al-Ansari et al. [15] | Right Frontoparietal, left Thalamus | | | | | ✓ |
15. | 2013, Wu et al. [16] | Left posterior cerebral artery | | | | ✓ | |
16. | 2014, Veloria et al. [17] | Left central pons and corpus callosum | | | | ✓ | ✓ |
17. | 2014, Yacoub et al. [18] | LMCA | ✓ | | ✓ | | |
18. | 2015, Kitchool et al.[19] | Right thalamus, posterior capsule | ✓ | ✓ | | | |
19. | 2015, Chu et al. [20] | Right Corona radiata, Centrum Semiovale, right cerebral hemisphere | ✓ | ✓ | | | |
20. | 2015, Villella et al. [21] | Left optic artery | ✓ | | | | |
21. | 2015, Dumitrascu et al. [22] | Left parietal lobe, bilateral centrum semiovale, right occipital | ✓ | ✓ | | | |
22. | 2015, Davogustto et al. [23] | Left centrum Semiovale | ✓ | | | | |
23. | 2016, Kamran et al. [24] | LMCA | ✓ | | ✓ | | | |
24. | 2016, Jo et al. [25] | RMCA | ✓ | ✓ | | | |
25. | 2016, Jo et al. [25] | LMCA | | | ✓ | | |
26. | 2017, Meireleset al. [26] | Right occipital Lobe, cerebellar hemispheres | | | ✓ | | |
27` | 2017, Vlacancich et al. [27] | Right precentral gyrus | ✓ | ✓ | | | |
LMCA= left middle cerebral artery, RMCA= right middle cerebral artery |