Table 1: Clinical features and hemodynamic parameters of patients and healthy controls (Age displayed as median and interquartile range, the other variables as means±SD). LED: L-DOPA equivalent dose calculated according to Tomlinson et al., 2010 [13], n.a.: not applicable,
*statistically significant comparison.
| PD Patients | Controls | p value |
Subjects (Male/Female) | 12 (9/3) | 11(11/0) | |
Age (years) | 62 (IQ: 51-77) | 59 (IQ: 48-65) | 0.347 |
Disease duration (years) | 5.8±2.4 | n.a. | |
Daily LED (mg) | 600±200 | n.a. | |
Hypertension (n. of cases, %) | 1 (8,3%) | 3 (27,3%) | 0.261 |
Smoking (yes/no) | 3 (25%) | 2 (18,2%) | 0.545 |
Mean BP (mmHg) | 99±17 | 86±12 | *0.033 |
Heart Rate | 80±15 | 63±9 | *0.002 |
Basal Mean Blood Flow Velocity (cm/s) | 43±15 | 52±8 | 0.069 |
BHI | 0.92±0.30 | 1.40±0.44 | *0.007 |