Table 1: Concentration reached by antifungal eye drops in vitreous humor.
Antifungical Drug Presentation Available Concentration in Vitreous Humour REF
Amphotericin B Amphotericin B deoxycholate eye drops (Fungizone®) 1.5 mg/ml No penetrates without prior epithelial debridement. [40,41]
Natamycin Natacyn® 50 mg/ml No penetrates without prior epithelial debridement [42]
Econazole Aurazole® 20 mg/ml 0.504 μg/ml [43]
Fluconazole Fluconazol eye drops 2 mg/ml 7.13μg/ml [44]
Voriconazole Voriconazole eye drops (Vfend®) 10 mg/ml 6μg/ml [45]