Table 3: Final population pharmacokinetic parameters of tacrolimus and bootstrap validation.
| Pharmacokinetic parameter | Final data estimate | Bootstrap |
| Pharmacokinetic parameter | Symbol (code) | Population mean | Standard error | Interindividual variability (%) | Median | 2.5th percentile | 97.5th percentile |
| Ka | θ1 | 4.5 | | | | |
| CL/F | θ2 | 19.5 | 2.15 | 11 | 19.352 | 14.997 | 23.944 |
| V/F | θ3 | 380 | 72.7 | 19 | 385.093 | 237.517 | 522.484 |
| SCR on V/F | θ4 | -0.22 | 0.06 | 27 | -0.2167 | -0.3352 | -0.1014 |
| SCR on CL/F | θ5 | -0.341 | 0.141 | 41 | -0.3489 | -0.6258 | -0.0569 |
| ALB on V/F | θ6 | 0.0821 | 0.028 | 34 | 0.04845 | 0.0271 | 0.13692 |
| Residual proportional variance (σ) | | 0.266 | | | | | |