Population Pharmacokinetic Analysis of Oral Tacrolimus in Patients with Glomerulonephritis : Table 1

Table 1: Baseline characteristics of patients (n=145).
Tx, Treatment; BWT, body weight; Conc, concentration; PCR, protein creatinine ration; WBC, white blood cell; HEMO, hemoglobin; HCT, hematocrit; PLT, platelet, BUN, blood urea nitrogen; SCR , serum creatinine level; GFR, estimated glomerular filtration rate; TPRO, total protein; ALB, serum albumin; TBIL, total bilirubin; AST, aspartate aminotransferase; ALT, alanine aminotransferase

	Male Gender, %	Age	Duration of Tx, days	BWT, kg	Conc, ng/mL	Urine PCr	WBC, K/μL	HEMO, g/dL	HCT, %	PLT, K/μL
Range	36.5	19 - 76	14-886	39 - 157	0-32.6	0.02 - 61.06	1.49 - 24.72	6.4 - 19.2	22.2-55	5 - 585
Mean		39.2	619.5	64	1.54	1.83	9.28	13.44	40.34	246.8
SD		13.7	518	15.7	2.95	3.0	3.38	1.75	4.7	67.7
	BUN, mg/dL	SCR, mg/dL	GFR, ml/min	CHOL, mg/dL	TPRO, mg/dL	ALB, mg/dL	Uric acid g/dL	TBIL, mg/dL	AST,IU/L	ALT,IU/L
Range	4 - 496	0.39 - 13.85	5-193	95 - 894	3.1 - 8.9	1.2 - 5.5	1.8 - 17.3	0.2 - 3.5	7-442	1 - 686
Mean	20.6	1.12	76.58	195.7	6.32	3.82	6.45	0.73	20.9	25.25
SD	16.7	0.8	30.57	67	0.83	0.59	1.8	0.33	14	26