Characterisation of the Ability of Carbamazepine for Processing It through Direct Compression Applying the New Expert System SeDeM : Table 3

Table 3: Test results for the API.

Incidence	Parameter	Symbol	U	Experimental value	Standard deviation	( r )	Mean incidence
Dimensions	Bulk density	ρ_bulk	g/ml	0.792	0.004	7.92	8.52
Dimensions	Tapped density	ρ_tapped	g/ml	0.911	0.003	9.11
Compressibility	Inter-particle porosity	Ie	-	0.165	0.009	1.37	1.9
	Carrindex	IC	%	13.08	0.681	2.61
	Cohesion index			34.4		1.72
Flowability/ powder flow	Hausner ratio	IH	-	1.15	0.000	9.25	3.69
	Rest angle	α	°	40.92	2.847	1.82
	Powder flow	t’'	S	∞	0.000	0
Lubrication/ stability	Losson drying	%HR	%	0.029	0.009	9.97	9.98
Lubrication/ stability	Hygroscopicity	%H	%	0.033	0.008	9.99
Dosage/ lubrication	Particles<45μm	%Pf	μm	0.053	0.025	9.90	6.45
Dosage/ lubrication	Homogenity Index	Iθ	-	0.006	0.003	3
					Parametric index	0.5
					Parametric profile (mean radius)
						5.55
					Good compression index (IGC)
						5.28