Table 1: A connection of SOS with biofilm dynamics.
Species Antimicrobials SOS-induced biofilm targets SOS Effects on biofilm References
Gram negative
P. aeruginosa Ofloxacin, norfloxacin and ceftazidime LexA? Increase [10]
P. aeruginosa Ofloxacin Ciprofloxacin Persisters Toxin/antitoxin locus, tisAB/istR LexA?
LexA		 Resistance
Resistance		 [93,94]
[66,70]
E. coli and P. aeruginosa Aminoglycosides LexA? Increase [6]
Vibrio cholerae Bile acids LexA? Increase [8]
P. aeruginosa Hydroxyurea, nalidixic acid LexA? Increase [11]
P. aeruginosa Pf4 prophage LexA? Superinfection (SI) variants and DNA release [43]
Multiple-species Pyocyanin Diversification [87]
E. coli Phage engineered to overproduce
LexA		 LexA Resistance [40]
Pf4 phage superinfection variant LexA Maturation [45]
P. aeruginosa Hydroxyurea, Ciprofloxacin Cell motility and attachment LexA
LexA		 Increase
Increase		 [12]
[14]
P. aeruginosa Mismatch repair system (MRS) Diversification, resistance evolution [89,92]
E. coli Ofloxacin Starvation LexA Tolerance [72]
E. coli Cell attachment LexA Increase [42]
E. coli Bacteriocin Colicin R LexA Decrease [84]
P. aeruginosa Bacteriocin Pyocin LexA Maturation [83,85,86]
E. coli and P. aeruginosa Tetracycline and cephradine LexA? Increase Plasmid transfer [57]
P. aeruginosa Suppression of phage-related genes by CRISPR LexA Decrease [52]
Gram positive
M. aviumwas Hydrogen peroxide LexA? Increase [9]
S. aureus Fibronectin-binding proteins LexA Increase [39]
S. aureus RecA LexA? Increase [38]
L. monocytogenes YneA LexA Increase [41]
L. monocytogenes Superoxide and hydroxyl radicals RecA LexA? Increase [71]