In Vitro Antifungal Activity of Cysteine Derivatives and their Combinations with Antifungal Agents Against Clinically Relevant Scedosporium species : Table 2

Table 2: The antifungal activity of cysteine and its derivatives against Scedosporium isolates.
^aCBS, Centraalbureau voor Schimmelcultures, Utrecht, The Netherlands.
^bDC, D-cysteine; LC, L-cysteine; LCME, L-cysteine-methyl ester hydrochloride; NIDC, N-isobutyryl-D-cysteine; NILC, N-isobutyryl-L-cysteine.

Species (Strain numbera)	Source	Mean MICs of cysteine and its derivativesb (μg/ml)
Species (Strain numbera)	Source	DC	LC	LCME	NIDC	NILC
S. aurantiacum (CBS 116910)	Wound exudate/Spain	>1024	>1024	512	>1024	1024
S. aurantiacum (CBS 136046)	Human lung/Australia	>1024	>1024	1024	>1024	>1024
S. aurantiacum (CBS 136047)	Soil/Australia	>1024	>1024	1024	>1024	>1024
S. aurantiacum (CBS 136049)	Soil/Austria	>1024	>1024	1024	>1024	>1024
S. boydii (CBS 117410)	Soil/Spain	>1024	>1024	1024	>1024	>1024
S. boydii (CBS 117432)	Sputum/France	>1024	>1024	1024	>1024	>1024
S. boydii (CBS 120157)	Human lung/France	>1024	>1024	1024	>1024	>1024
P. angusta (CBS 254.72)	Sewage/USA	>1024	>1024	1024	>1024	>1024
P. ellipsoidea (CBS 301.79)	Dung/The Netherlands	>1024	>1024	>1024	>1024	>1024
MIC range		>1024	>1024	512 - >1024	>1024	1024 - >1024