| S.No | Main steps for improving door-to-needle times (derived from [15]) |
| 01 | Hospital pre-notification by emergency medical system |
| 02 | Rapid triage protocol and activation of stroke team |
| 03 | Availability of stroke protocols |
| 04 | Rapid access to IV cannulation |
| 05 | Rapid imaging and laboratory tests |
| 06 | Mixing rtPA when the patient is eligible and rapid iv administration |
| 07 | Data Registry and periodic data review by the whole stroke team |