| Symptoms | Signs |
| Fever | Apnea, cyanosis |
| Decreased feeding | Pallor |
| Failure to thrive | Respiratory distress, Nasal flaring |
| Projectile or bilious vomiting, blood in stools, watery diarrhea | Weight < 5th Percentile |
| Lethargies | Bulging tense fontanels,Macrocephaly |
| Irregular breathing or breathing difficulty | Bruises, petechial hemorrhages |
| Abnormal movements | Meningism, hypotonia |